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Toward effective probiotics for autism and other neurodevelopmental disorders.
Gilbert, Jack A; Krajmalnik-Brown, Rosa; Porazinska, Dorota L; Weiss, Sophie J; Knight, Rob.
Afiliación
  • Gilbert JA; Institute for Genomic and Systems Biology, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60439, USA; Department of Ecology and Evolution, University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637, USA.
  • Krajmalnik-Brown R; Swette Center for Environmental Biotechnology Biodesign Institute at Arizona State University, 1001 South McAllister Avenue, Tempe, AZ 85287-5701, USA; School of Sustainable Engineering and the Built Environment, Arizona State University, Tempe, AZ 85287-5701, USA.
  • Porazinska DL; Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado at Boulder, Boulder, CO 80309, USA.
  • Weiss SJ; Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado at Boulder, Boulder, CO 80309, USA.
  • Knight R; Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado at Boulder, Boulder, CO 80309, USA; Howard Hughes Medical Institute, Boulder, CO 80309, USA. Electronic address: rob.knight@colorado.edu.
Cell ; 155(7): 1446-8, 2013 Dec 19.
Article en En | MEDLINE | ID: mdl-24360269
ABSTRACT
Hsaio and colleagues link gut microbes to autism spectrum disorders (ASD) in a mouse model. They show that ASD symptoms are triggered by compositional and structural shifts of microbes and associated metabolites, but symptoms are relieved by a Bacteroides fragilis probiotic. Thus probiotics may provide therapeutic strategies for neurodevelopmental disorders.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trastornos Generalizados del Desarrollo Infantil / Tracto Gastrointestinal Límite: Animals / Female / Humans Idioma: En Revista: Cell Año: 2013 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trastornos Generalizados del Desarrollo Infantil / Tracto Gastrointestinal Límite: Animals / Female / Humans Idioma: En Revista: Cell Año: 2013 Tipo del documento: Article País de afiliación: Estados Unidos