Addiction treatment trials: how gender, race/ethnicity, and age relate to ongoing participation and retention in clinical trials.
Subst Abuse Rehabil
; 2: 205-18, 2011.
Article
en En
| MEDLINE
| ID: mdl-24474858
ABSTRACT
INTRODUCTION:
Historically, racial and ethnic minority populations have been underrepresented in clinical research, and the recruitment and retention of women and ethnic minorities in clinical trials has been a significant challenge for investigators. The National Drug Abuse Treatment Clinical Trials Network (CTN) conducts clinical trials in real-life settings and regularly monitors a number of variables critical to clinical trial implementation, including the retention and demographics of participants.PURPOSE:
The examination of gender, race/ethnicity, and age group differences with respect to retention characteristics in CTN trials.METHODS:
Reports for 24 completed trials that recruited over 11,000 participants were reviewed, and associations of gender, race/ethnicity, and age group characteristics were examined along with the rate of treatment exposure, the proportion of follow-up assessments obtained, and the availability of primary outcome measure(s).RESULTS:
Analysis of the CTN data did not indicate statistical differences in retention across gender or race/ethnicity groups; however, retention rates increased for older participants.CONCLUSION:
These results are based on a large sample of patients with substance use disorders recruited from a treatment-seeking population. The findings demonstrate that younger participants are less likely than older adults to be retained in clinical trials.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Subst Abuse Rehabil
Año:
2011
Tipo del documento:
Article
País de afiliación:
Estados Unidos