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Sustained inhibition of receptor tyrosine kinases and macrophage depletion by PLX3397 and rapamycin as a potential new approach for the treatment of MPNSTs.
Patwardhan, Parag P; Surriga, Oliver; Beckman, Michael J; de Stanchina, Elisa; Dematteo, Ronald P; Tap, William D; Schwartz, Gary K.
Afiliación
  • Patwardhan PP; Authors' Affiliations: Jennifer Goodman Linn Laboratory of New Drug Development, Department of Medicine, Department of Molecular Pharmacology and Chemistry, Department of Surgery, Memorial Sloan Kettering Cancer Center; and Division of Hematology/Oncology, Columbia University Medical Center, New Yor
  • Surriga O; Authors' Affiliations: Jennifer Goodman Linn Laboratory of New Drug Development, Department of Medicine, Department of Molecular Pharmacology and Chemistry, Department of Surgery, Memorial Sloan Kettering Cancer Center; and Division of Hematology/Oncology, Columbia University Medical Center, New Yor
  • Beckman MJ; Authors' Affiliations: Jennifer Goodman Linn Laboratory of New Drug Development, Department of Medicine, Department of Molecular Pharmacology and Chemistry, Department of Surgery, Memorial Sloan Kettering Cancer Center; and Division of Hematology/Oncology, Columbia University Medical Center, New Yor
  • de Stanchina E; Authors' Affiliations: Jennifer Goodman Linn Laboratory of New Drug Development, Department of Medicine, Department of Molecular Pharmacology and Chemistry, Department of Surgery, Memorial Sloan Kettering Cancer Center; and Division of Hematology/Oncology, Columbia University Medical Center, New Yor
  • Dematteo RP; Authors' Affiliations: Jennifer Goodman Linn Laboratory of New Drug Development, Department of Medicine, Department of Molecular Pharmacology and Chemistry, Department of Surgery, Memorial Sloan Kettering Cancer Center; and Division of Hematology/Oncology, Columbia University Medical Center, New Yor
  • Tap WD; Authors' Affiliations: Jennifer Goodman Linn Laboratory of New Drug Development, Department of Medicine, Department of Molecular Pharmacology and Chemistry, Department of Surgery, Memorial Sloan Kettering Cancer Center; and Division of Hematology/Oncology, Columbia University Medical Center, New Yor
  • Schwartz GK; Authors' Affiliations: Jennifer Goodman Linn Laboratory of New Drug Development, Department of Medicine, Department of Molecular Pharmacology and Chemistry, Department of Surgery, Memorial Sloan Kettering Cancer Center; and Division of Hematology/Oncology, Columbia University Medical Center, New Yor
Clin Cancer Res ; 20(12): 3146-58, 2014 Jun 15.
Article en En | MEDLINE | ID: mdl-24718867
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirroles / Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogénicas c-kit / Receptor beta de Factor de Crecimiento Derivado de Plaquetas / Aminopiridinas / Macrófagos / Neurilemoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2014 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirroles / Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogénicas c-kit / Receptor beta de Factor de Crecimiento Derivado de Plaquetas / Aminopiridinas / Macrófagos / Neurilemoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2014 Tipo del documento: Article