Thalidomide mimics uridine binding to an aromatic cage in cereblon.

Hartmann, Marcus D; Boichenko, Iuliia; Coles, Murray; Zanini, Fabio; Lupas, Andrei N; Hernandez Alvarez, Birte

Hartmann, Marcus D; Boichenko, Iuliia; Coles, Murray; Zanini, Fabio; Lupas, Andrei N; Hernandez Alvarez, Birte.

Afiliación

Hartmann MD; Department of Protein Evolution, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.
Boichenko I; Department of Protein Evolution, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.
Coles M; Department of Protein Evolution, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.
Zanini F; Evolutionary Dynamics and Biophysics Group, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.
Lupas AN; Department of Protein Evolution, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.
Hernandez Alvarez B; Department of Protein Evolution, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany. Electronic address: birte.hernandez@tuebingen.mpg.de.

J Struct Biol ; 188(3): 225-32, 2014 Dec.

Article en En | MEDLINE | ID: mdl-25448889

Asunto(s)

Antineoplásicos/farmacología; Péptido Hidrolasas/metabolismo; Talidomida/farmacología; Uridina/metabolismo; Sitios de Unión; Escherichia coli

Palabras clave

IMiD; Immunomodulatory drug; Pomalyst; Revlimid

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptido Hidrolasas / Talidomida / Uridina / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: J Struct Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2014 Tipo del documento: Article País de afiliación: Alemania

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google