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Characterization of phase I metabolism of resibufogenin and evaluation of the metabolic effects on its antitumor activity and toxicity.
Ning, Jing; Yu, Zhen-Long; Hu, Liang-Hai; Wang, Chao; Huo, Xiao-Kui; Deng, Sa; Hou, Jie; Wu, Jing-Jing; Ge, Guang-Bo; Ma, Xiao-Chi; Yang, Ling.
Afiliación
  • Ning J; Research Institute of Integrated Traditional and Western Medicine, College of Pharmacy, Dalian Medical University, Dalian, China (J.N., Z.-L.Y., C.W., X.-K H., S.D., J.H., X.-C.M.); Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China
  • Yu ZL; Research Institute of Integrated Traditional and Western Medicine, College of Pharmacy, Dalian Medical University, Dalian, China (J.N., Z.-L.Y., C.W., X.-K H., S.D., J.H., X.-C.M.); Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China
  • Hu LH; Research Institute of Integrated Traditional and Western Medicine, College of Pharmacy, Dalian Medical University, Dalian, China (J.N., Z.-L.Y., C.W., X.-K H., S.D., J.H., X.-C.M.); Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China
  • Wang C; Research Institute of Integrated Traditional and Western Medicine, College of Pharmacy, Dalian Medical University, Dalian, China (J.N., Z.-L.Y., C.W., X.-K H., S.D., J.H., X.-C.M.); Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China
  • Huo XK; Research Institute of Integrated Traditional and Western Medicine, College of Pharmacy, Dalian Medical University, Dalian, China (J.N., Z.-L.Y., C.W., X.-K H., S.D., J.H., X.-C.M.); Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China
  • Deng S; Research Institute of Integrated Traditional and Western Medicine, College of Pharmacy, Dalian Medical University, Dalian, China (J.N., Z.-L.Y., C.W., X.-K H., S.D., J.H., X.-C.M.); Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China
  • Hou J; Research Institute of Integrated Traditional and Western Medicine, College of Pharmacy, Dalian Medical University, Dalian, China (J.N., Z.-L.Y., C.W., X.-K H., S.D., J.H., X.-C.M.); Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China
  • Wu JJ; Research Institute of Integrated Traditional and Western Medicine, College of Pharmacy, Dalian Medical University, Dalian, China (J.N., Z.-L.Y., C.W., X.-K H., S.D., J.H., X.-C.M.); Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China
  • Ge GB; Research Institute of Integrated Traditional and Western Medicine, College of Pharmacy, Dalian Medical University, Dalian, China (J.N., Z.-L.Y., C.W., X.-K H., S.D., J.H., X.-C.M.); Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China
  • Ma XC; Research Institute of Integrated Traditional and Western Medicine, College of Pharmacy, Dalian Medical University, Dalian, China (J.N., Z.-L.Y., C.W., X.-K H., S.D., J.H., X.-C.M.); Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China
  • Yang L; Research Institute of Integrated Traditional and Western Medicine, College of Pharmacy, Dalian Medical University, Dalian, China (J.N., Z.-L.Y., C.W., X.-K H., S.D., J.H., X.-C.M.); Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China
Drug Metab Dispos ; 43(3): 299-308, 2015 Mar.
Article en En | MEDLINE | ID: mdl-25504504
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bufanólidos / Fase I de la Desintoxicación Metabólica / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Drug Metab Dispos Asunto de la revista: FARMACOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bufanólidos / Fase I de la Desintoxicación Metabólica / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Drug Metab Dispos Asunto de la revista: FARMACOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: China