Proteasome regulation of the chromodomain protein MRG-1 controls the balance between proliferative fate and differentiation in the C. elegans germ line.

Gupta, Pratyush; Leahul, Lindsay; Wang, Xin; Wang, Chris; Bakos, Brendan; Jasper, Katie; Hansen, Dave

Gupta, Pratyush; Leahul, Lindsay; Wang, Xin; Wang, Chris; Bakos, Brendan; Jasper, Katie; Hansen, Dave.

Afiliación

Gupta P; Department of Biological Sciences, University of Calgary, 2500 University Drive, Calgary, Alberta, Canada T2N 1N4.
Leahul L; Department of Biological Sciences, University of Calgary, 2500 University Drive, Calgary, Alberta, Canada T2N 1N4.
Wang X; Department of Biological Sciences, University of Calgary, 2500 University Drive, Calgary, Alberta, Canada T2N 1N4.
Wang C; Department of Biological Sciences, University of Calgary, 2500 University Drive, Calgary, Alberta, Canada T2N 1N4.
Bakos B; Department of Biological Sciences, University of Calgary, 2500 University Drive, Calgary, Alberta, Canada T2N 1N4.
Jasper K; Department of Biological Sciences, University of Calgary, 2500 University Drive, Calgary, Alberta, Canada T2N 1N4.
Hansen D; Department of Biological Sciences, University of Calgary, 2500 University Drive, Calgary, Alberta, Canada T2N 1N4 dhansen@ucalgary.ca.

Development ; 142(2): 291-302, 2015 Jan 15.

Article en En | MEDLINE | ID: mdl-25564623

Asunto(s)

Proteínas de Caenorhabditis elegans/metabolismo; Caenorhabditis elegans/crecimiento & desarrollo; Diferenciación Celular/fisiología; Proliferación Celular/fisiología; Células Germinativas/crecimiento & desarrollo; Complejo de la Endopetidasa Proteasomal/metabolismo; Ubiquitina-Proteína Ligasas/metabolismo; Animales; Western Blotting; Caenorhabditis elegans/metabolismo; Proteínas Portadoras/metabolismo; Biología Computacional; Células Germinativas/metabolismo; Inmunoprecipitación; Interferencia de ARN; Técnicas del Sistema de Dos Híbridos

Palabras clave

Caenorhabditis elegans; E3 ubiquitin ligase; MRG-1; Proteasomal degradation; RFP-1; Stem cell proliferative fate; Substrate recognition subunit

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diferenciación Celular / Caenorhabditis elegans / Proteínas de Caenorhabditis elegans / Ubiquitina-Proteína Ligasas / Complejo de la Endopetidasa Proteasomal / Proliferación Celular / Células Germinativas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Development Asunto de la revista: BIOLOGIA / EMBRIOLOGIA Año: 2015 Tipo del documento: Article

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