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IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction.
Nold-Petry, Claudia A; Lo, Camden Y; Rudloff, Ina; Elgass, Kirstin D; Li, Suzhao; Gantier, Michael P; Lotz-Havla, Amelie S; Gersting, Søren W; Cho, Steven X; Lao, Jason C; Ellisdon, Andrew M; Rotter, Björn; Azam, Tania; Mangan, Niamh E; Rossello, Fernando J; Whisstock, James C; Bufler, Philip; Garlanda, Cecilia; Mantovani, Alberto; Dinarello, Charles A; Nold, Marcel F.
Afiliación
  • Nold-Petry CA; 1] Ritchie Centre, MIMR-PHI Institute of Medical Research, Melbourne, Victoria, Australia. [2] Department of Paediatrics, Monash University, Melbourne, Australia.
  • Lo CY; 1] Ritchie Centre, MIMR-PHI Institute of Medical Research, Melbourne, Victoria, Australia. [2] Monash Micro Imaging, Monash University, Melbourne, Australia.
  • Rudloff I; 1] Ritchie Centre, MIMR-PHI Institute of Medical Research, Melbourne, Victoria, Australia. [2] Department of Paediatrics, Monash University, Melbourne, Australia.
  • Elgass KD; Monash Micro Imaging, Monash University, Melbourne, Australia.
  • Li S; Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA.
  • Gantier MP; 1] Centre for Cancer Research, MIMR-PHI Institute of Medical Research, Melbourne, Victoria, Australia. [2] Department of Molecular and Translational Science, Monash University, Melbourne, Australia.
  • Lotz-Havla AS; Molecular Pediatrics, Ludwig-Maximilians University, Munich, Germany.
  • Gersting SW; Molecular Pediatrics, Ludwig-Maximilians University, Munich, Germany.
  • Cho SX; 1] Ritchie Centre, MIMR-PHI Institute of Medical Research, Melbourne, Victoria, Australia. [2] Department of Paediatrics, Monash University, Melbourne, Australia.
  • Lao JC; 1] Ritchie Centre, MIMR-PHI Institute of Medical Research, Melbourne, Victoria, Australia. [2] Department of Paediatrics, Monash University, Melbourne, Australia.
  • Ellisdon AM; 1] Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia. [2] Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Melbourne, Australia.
  • Rotter B; GenXPro, Frankfurt, Germany.
  • Azam T; Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA.
  • Mangan NE; 1] Department of Molecular and Translational Science, Monash University, Melbourne, Australia. [2] Centre for Innate Immunity and Infectious Diseases, MIMR-PHI Institute of Medical Research, Melbourne, Australia.
  • Rossello FJ; Victorian Bioinformatics Consortium, Monash University, Melbourne, Australia.
  • Whisstock JC; 1] Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia. [2] Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Melbourne, Australia.
  • Bufler P; Department of Pediatrics, Dr. von Hauner Children's Hospital, Ludwig-Maximilians University, Munich, Germany.
  • Garlanda C; Humanitas Clinical and Research Center, Rozzano, Italy.
  • Mantovani A; 1] Humanitas Clinical and Research Center, Rozzano, Italy. [2] Humanitas University, Rozzano, Italy.
  • Dinarello CA; 1] Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA. [2] Radboud University Medical Centre, Nijmegen, the Netherlands.
  • Nold MF; 1] Ritchie Centre, MIMR-PHI Institute of Medical Research, Melbourne, Victoria, Australia. [2] Department of Paediatrics, Monash University, Melbourne, Australia. [3] Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA.
Nat Immunol ; 16(4): 354-65, 2015 Apr.
Article en En | MEDLINE | ID: mdl-25729923
Asunto(s)
Subunidad alfa del Receptor de Interleucina-18/inmunología; Interleucina-1/inmunología; Leucocitos Mononucleares/inmunología; Receptores de Interleucina-1/inmunología; Transducción de Señal/inmunología; Animales; Línea Celular; Regulación de la Expresión Génica; Humanos; Inmunidad Innata; Inflamación/genética; Inflamación/inmunología; Inflamación/patología; Interleucina-1/genética; Subunidad alfa del Receptor de Interleucina-18/antagonistas & inhibidores; Subunidad alfa del Receptor de Interleucina-18/genética; Leucocitos Mononucleares/efectos de los fármacos; Leucocitos Mononucleares/patología; Lipopolisacáridos/farmacología; Quinasas Quinasa Quinasa PAM/genética; Quinasas Quinasa Quinasa PAM/inmunología; Ratones; Ratones Transgénicos; FN-kappa B/genética; FN-kappa B/inmunología; Fosfohidrolasa PTEN/genética; Fosfohidrolasa PTEN/inmunología; Unión Proteica; Proteínas Proto-Oncogénicas/genética; Proteínas Proto-Oncogénicas/inmunología; Proteínas Proto-Oncogénicas c-fyn/genética; Proteínas Proto-Oncogénicas c-fyn/inmunología; ARN Interferente Pequeño/genética; ARN Interferente Pequeño/inmunología; Proteínas de Unión al ARN/genética; Proteínas de Unión al ARN/inmunología; Proteínas Tirosina Quinasas Receptoras/genética; Proteínas Tirosina Quinasas Receptoras/inmunología; Receptores de Interleucina-1/antagonistas & inhibidores; Receptores de Interleucina-1/deficiencia; Receptores de Interleucina-1/genética; Factor de Transcripción STAT3/genética; Factor de Transcripción STAT3/inmunología; Serina-Treonina Quinasas TOR/genética; Serina-Treonina Quinasas TOR/inmunología; Tirosina Quinasa c-Mer
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucocitos Mononucleares / Transducción de Señal / Interleucina-1 / Receptores de Interleucina-1 / Subunidad alfa del Receptor de Interleucina-18 Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Australia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucocitos Mononucleares / Transducción de Señal / Interleucina-1 / Receptores de Interleucina-1 / Subunidad alfa del Receptor de Interleucina-18 Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Australia