Antibiotic profiling of Clostridium difficile ribotype 176--A multidrug resistant relative to C. difficile ribotype 027.

Krutova, Marcela; Matejkova, Jana; Tkadlec, Jan; Nyc, Otakar

Krutova, Marcela; Matejkova, Jana; Tkadlec, Jan; Nyc, Otakar.

Afiliación

Krutova M; Department of Medical Microbiology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital in Motol, Czech Republic; DNA laboratory, Department of Paediatric Neurology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital in Motol, Czech Republic. Elec
Matejkova J; Department of Medical Microbiology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital in Motol, Czech Republic.
Tkadlec J; Department of Medical Microbiology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital in Motol, Czech Republic.
Nyc O; Department of Medical Microbiology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital in Motol, Czech Republic.

Anaerobe ; 36: 88-90, 2015 Dec.

Article en En | MEDLINE | ID: mdl-26256807

ABSTRACT

ABSTRACT

Antibiotic profiling of twenty Czech Clostridium difficile PCR-ribotype 176 isolates revealed a high level of resistance to erythromycin, ciprofloxacin and moxifloxacin (n = 20) and to rifampicin (n = 13). Accumulation of resistance mechanisms to multiple antibiotics highlight that PCR-ribotype 176 belong to problematic epidemic strains.

Asunto(s)

Antibacterianos/farmacología; Clostridioides difficile/efectos de los fármacos; Farmacorresistencia Bacteriana Múltiple; Enterocolitis Seudomembranosa/microbiología; Proteínas Bacterianas/genética; Proteínas Bacterianas/metabolismo; Secuencia de Bases; Clostridioides difficile/clasificación; Clostridioides difficile/genética; Clostridioides difficile/aislamiento & purificación; República Checa; Humanos; Datos de Secuencia Molecular; Mutación; Ribotipificación

Palabras clave

Clostridium difficile; Erythromycin; Moxifloxacin; PCR-ribotype 176; Resistance; Rifampicin; Thr82Ile

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enterocolitis Seudomembranosa / Clostridioides difficile / Farmacorresistencia Bacteriana Múltiple / Antibacterianos Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Anaerobe Año: 2015 Tipo del documento: Article

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