RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself.

Liddicoat, Brian J; Piskol, Robert; Chalk, Alistair M; Ramaswami, Gokul; Higuchi, Miyoko; Hartner, Jochen C; Li, Jin Billy; Seeburg, Peter H; Walkley, Carl R

Liddicoat, Brian J; Piskol, Robert; Chalk, Alistair M; Ramaswami, Gokul; Higuchi, Miyoko; Hartner, Jochen C; Li, Jin Billy; Seeburg, Peter H; Walkley, Carl R.

Afiliación

Liddicoat BJ; St. Vincent's Institute of Medical Research, Fitzroy, Victoria 3065, Australia. Department of Medicine, St. Vincent's Hospital, University of Melbourne, Fitzroy, Victoria 3065, Australia.
Piskol R; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
Chalk AM; St. Vincent's Institute of Medical Research, Fitzroy, Victoria 3065, Australia. Department of Medicine, St. Vincent's Hospital, University of Melbourne, Fitzroy, Victoria 3065, Australia.
Ramaswami G; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
Higuchi M; Department of Molecular Neurobiology, Max Planck Institute for Medical Research, 69120 Heidelberg, Germany.
Hartner JC; Taconic Biosciences, 51063 Cologne, Germany.
Li JB; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
Seeburg PH; Department of Molecular Neurobiology, Max Planck Institute for Medical Research, 69120 Heidelberg, Germany.
Walkley CR; St. Vincent's Institute of Medical Research, Fitzroy, Victoria 3065, Australia. Department of Medicine, St. Vincent's Hospital, University of Melbourne, Fitzroy, Victoria 3065, Australia. cwalkley@svi.edu.au.

Science ; 349(6252): 1115-20, 2015 Sep 04.

Article en En | MEDLINE | ID: mdl-26275108

Asunto(s)

Adenosina Desaminasa/metabolismo; ARN Helicasas DEAD-box/metabolismo; Pérdida del Embrión/genética; Edición de ARN; ARN Bicatenario/metabolismo; Regiones no Traducidas 3'; Adenosina/genética; Adenosina Desaminasa/genética; Animales; ARN Helicasas DEAD-box/genética; Eliminación de Gen; Técnicas de Sustitución del Gen; Inosina/genética; Helicasa Inducida por Interferón IFIH1; Ratones; Ratones Mutantes; Mutación; Conformación de Ácido Nucleico; ARN Bicatenario/química; Transcripción Genética

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ARN Bicatenario / Adenosina Desaminasa / Edición de ARN / Pérdida del Embrión / ARN Helicasas DEAD-box Límite: Animals Idioma: En Revista: Science Año: 2015 Tipo del documento: Article País de afiliación: Australia

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