Dapsone in the treatment of pemphigus vulgaris: adverse effects and its importance as a corticosteroid sparing agent.
An Bras Dermatol
; 90(3 Suppl 1): 51-4, 2015.
Article
en En
| MEDLINE
| ID: mdl-26312673
ABSTRACT
Pemphigus vulgaris is an autoimmune disease characterized by suprabasal blisters with acantholysis, which has a fatal course in a large number of untreated patients. Systemic corticosteroid therapy is considered first-line therapy. Adjuvant treatment with the goal of sparing corticosteroids include, among others, dapsone. This drug is not without side effects and its use requires clinical and laboratory control. We present a patient with PV initially managed with suboptimal dose of prednisone, evolving into drug-induced hepatitis after introduction of dapsone.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Prednisona
/
Pénfigo
/
Dapsona
/
Antagonistas del Ácido Fólico
/
Glucocorticoides
Tipo de estudio:
Etiology_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
An Bras Dermatol
Año:
2015
Tipo del documento:
Article
País de afiliación:
Brasil