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Targeted γ-Secretase Inhibition To Control the Notch Pathway in Renal Diseases.
Juillerat-Jeanneret, Lucienne; Flohr, Alexander; Schneider, Manfred; Walter, Isabelle; Wyss, Jean-Christophe; Kumar, Rajesh; Golshayan, Dela; Aebi, Johannes D.
Afiliación
  • Juillerat-Jeanneret L; Transplantation Center, Department of Medicine, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL) , CH-1011 Lausanne, Switzerland.
  • Flohr A; University Institute of Pathology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL) , CH-1011 Lausanne, Switzerland.
  • Schneider M; Medicinal Chemistry, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Walter I; Medicinal Chemistry, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Wyss JC; Medicinal Chemistry, Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , CH-4070 Basel, Switzerland.
  • Kumar R; Transplantation Center, Department of Medicine, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL) , CH-1011 Lausanne, Switzerland.
  • Golshayan D; Transplantation Center, Department of Medicine, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL) , CH-1011 Lausanne, Switzerland.
  • Aebi JD; Transplantation Center, Department of Medicine, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL) , CH-1011 Lausanne, Switzerland.
J Med Chem ; 58(20): 8097-109, 2015 Oct 22.
Article en En | MEDLINE | ID: mdl-26421850

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fármacos Renales / Receptores Notch / Secretasas de la Proteína Precursora del Amiloide / Enfermedades Renales Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Suiza

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fármacos Renales / Receptores Notch / Secretasas de la Proteína Precursora del Amiloide / Enfermedades Renales Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Suiza