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The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter.
Gijselinck, I; Van Mossevelde, S; van der Zee, J; Sieben, A; Engelborghs, S; De Bleecker, J; Ivanoiu, A; Deryck, O; Edbauer, D; Zhang, M; Heeman, B; Bäumer, V; Van den Broeck, M; Mattheijssens, M; Peeters, K; Rogaeva, E; De Jonghe, P; Cras, P; Martin, J-J; de Deyn, P P; Cruts, M; Van Broeckhoven, C.
Afiliación
  • Gijselinck I; Neurodegenerative Brain Diseases Group VIB Department of Molecular Genetics, Antwerp, Belgium.
  • Van Mossevelde S; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
  • van der Zee J; Neurodegenerative Brain Diseases Group VIB Department of Molecular Genetics, Antwerp, Belgium.
  • Sieben A; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
  • Engelborghs S; Neurodegenerative Brain Diseases Group VIB Department of Molecular Genetics, Antwerp, Belgium.
  • De Bleecker J; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
  • Ivanoiu A; Neurodegenerative Brain Diseases Group VIB Department of Molecular Genetics, Antwerp, Belgium.
  • Deryck O; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
  • Edbauer D; Department of Neurology, University Hospital Ghent and University of Ghent, Ghent, Belgium.
  • Zhang M; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
  • Heeman B; Department of Neurology and Memory Clinic, Hospital Network Antwerp Middelheim and Hoge Beuken, Antwerp, Belgium.
  • Bäumer V; Department of Neurology, University Hospital Ghent and University of Ghent, Ghent, Belgium.
  • Van den Broeck M; Department of Neurology, Saint-Luc University Hospital and Institute of Neuroscience, Université Catholique de Louvain, Brussels, Belgium.
  • Mattheijssens M; Department of Neurology, General Hospital Sint-Jan Brugge-Oostende, Bruges, Belgium.
  • Peeters K; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Rogaeva E; Adolf Butenandt Institute, Biochemistry and Munich Cluster of Systems Neurology (SyNergy), Ludwig-Maximilians University Munich, Munich, Germany.
  • De Jonghe P; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
  • Cras P; Neurodegenerative Brain Diseases Group VIB Department of Molecular Genetics, Antwerp, Belgium.
  • Martin JJ; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
  • de Deyn PP; Neurodegenerative Brain Diseases Group VIB Department of Molecular Genetics, Antwerp, Belgium.
  • Cruts M; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
  • Van Broeckhoven C; Neurodegenerative Brain Diseases Group VIB Department of Molecular Genetics, Antwerp, Belgium.
Mol Psychiatry ; 21(8): 1112-24, 2016 08.
Article en En | MEDLINE | ID: mdl-26481318
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2016 Tipo del documento: Article País de afiliación: Bélgica
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2016 Tipo del documento: Article País de afiliación: Bélgica