CTLA-4 and Autoimmunity: New Twists in the Tale.

Walker, Lucy S K

Walker, Lucy S K.

Afiliación

Walker LSK; Institute for Immunity & Transplantation, University College London Division of Infection & Immunity, Royal Free Campus, London, NW3 2PF, UK. Electronic address: lucy.walker@ucl.ac.uk.

Trends Immunol ; 36(12): 760-762, 2015 Dec.

Article en En | MEDLINE | ID: mdl-26596798

ABSTRACT

ABSTRACT

CTLA-4 has long been associated with control of autoimmunity. A recent study by Sharpe and colleagues explores this relationship in a model that enables conditional deletion of CTLA-4 in adult mice, with some surprising new conclusions.

Asunto(s)

Autoinmunidad/inmunología; Antígeno CTLA-4/genética; Encefalomielitis Autoinmune Experimental/inmunología; Linfocitos T Reguladores/inmunología; Animales

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autoinmunidad / Linfocitos T Reguladores / Encefalomielitis Autoinmune Experimental / Antígeno CTLA-4 Límite: Animals Idioma: En Revista: Trends Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2015 Tipo del documento: Article

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