Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity.

Xia, Pengyan; Ye, Buqing; Wang, Shuo; Zhu, Xiaoxiao; Du, Ying; Xiong, Zhen; Tian, Yong; Fan, Zusen

Xia, Pengyan; Ye, Buqing; Wang, Shuo; Zhu, Xiaoxiao; Du, Ying; Xiong, Zhen; Tian, Yong; Fan, Zusen.

Afiliación

Xia P; Key Laboratory of Infection and Immunity of the Chinese Academy of Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Ye B; Key Laboratory of Infection and Immunity of the Chinese Academy of Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Wang S; Key Laboratory of Infection and Immunity of the Chinese Academy of Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Zhu X; Animal Research Center, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Du Y; Key Laboratory of Infection and Immunity of the Chinese Academy of Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Xiong Z; Key Laboratory of Infection and Immunity of the Chinese Academy of Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Tian Y; University of Chinese Academy of Sciences, Beijing, China.
Fan Z; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

Nat Immunol ; 17(4): 369-78, 2016 Apr.

Article en En | MEDLINE | ID: mdl-26829768

Asunto(s)

Carboxipeptidasas/genética; Infecciones por Virus ADN/metabolismo; ADN Viral/inmunología; Nucleotidiltransferasas/metabolismo; Péptido Sintasas/metabolismo; Animales; Citosol; Virus ADN/genética; Técnica del Anticuerpo Fluorescente; Herpes Simple/metabolismo; Inmunoprecipitación; Factor 3 Regulador del Interferón/inmunología; Interferones/inmunología; Ratones; Ratones Noqueados; Nucleótidos Cíclicos/biosíntesis; Nucleotidiltransferasas/inmunología; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Simplexvirus/genética; Vaccinia/metabolismo; Virus Vaccinia/genética

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptido Sintasas / ADN Viral / Carboxipeptidasas / Infecciones por Virus ADN / Nucleotidiltransferasas Límite: Animals Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: China

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