Mouse models for ROS1-fusion-positive lung cancers and their application to the analysis of multikinase inhibitor efficiency.

Inoue, Maki; Toki, Hideaki; Matsui, Junko; Togashi, Yuki; Dobashi, Akito; Fukumura, Ryutaro; Gondo, Yoichi; Minowa, Osamu; Tanaka, Norio; Mori, Seiichi; Takeuchi, Kengo; Noda, Tetsuo

Inoue, Maki; Toki, Hideaki; Matsui, Junko; Togashi, Yuki; Dobashi, Akito; Fukumura, Ryutaro; Gondo, Yoichi; Minowa, Osamu; Tanaka, Norio; Mori, Seiichi; Takeuchi, Kengo; Noda, Tetsuo.

Afiliación

Inoue M; Team for Advanced Development and Evaluation of Human Disease Models, RIKEN BioResource Center, Tsukuba 305-0074, Japan, Division of Cell Biology.
Toki H; Team for Advanced Development and Evaluation of Human Disease Models, RIKEN BioResource Center, Tsukuba 305-0074, Japan.
Matsui J; Team for Advanced Development and Evaluation of Human Disease Models, RIKEN BioResource Center, Tsukuba 305-0074, Japan.
Togashi Y; Pathology Project for Molecular Targets and Division of Pathology, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Dobashi A; Pathology Project for Molecular Targets and.
Fukumura R; Mutagenesis and Genomics Team, RIKEN BioResource Center, Tsukuba 305-0074, Japan and.
Gondo Y; Mutagenesis and Genomics Team, RIKEN BioResource Center, Tsukuba 305-0074, Japan and.
Minowa O; Team for Advanced Development and Evaluation of Human Disease Models, RIKEN BioResource Center, Tsukuba 305-0074, Japan.
Tanaka N; Project for Development of Innovative Research on Cancer Therapeutics, The Genome Center, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Mori S; Project for Development of Innovative Research on Cancer Therapeutics, The Genome Center, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Takeuchi K; Pathology Project for Molecular Targets and Division of Pathology, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
Noda T; Team for Advanced Development and Evaluation of Human Disease Models, RIKEN BioResource Center, Tsukuba 305-0074, Japan, Division of Cell Biology, tnoda@jfcr.or.jp.

Carcinogenesis ; 37(5): 452-60, 2016 05.

Article en En | MEDLINE | ID: mdl-26964870

Asunto(s)

Neoplasias Hepáticas Experimentales/genética; Neoplasias Pulmonares/genética; Proteínas de Fusión Oncogénica/genética; Inhibidores de Proteínas Quinasas/farmacología; Proteínas Tirosina Quinasas/genética; Proteínas Proto-Oncogénicas/genética; Adenocarcinoma/genética; Adenocarcinoma/patología; Adenocarcinoma del Pulmón; Adenoma/genética; Adenoma/patología; Administración Oral; Animales; Antígenos de Diferenciación de Linfocitos B/genética; Crizotinib; Fusión Génica; Antígenos de Histocompatibilidad Clase II/genética; Humanos; Neoplasias Hepáticas Experimentales/tratamiento farmacológico; Neoplasias Hepáticas Experimentales/patología; Neoplasias Pulmonares/patología; Ratones Endogámicos C57BL; Ratones Transgénicos; Proteínas de Fusión Oncogénica/antagonistas & inhibidores; Inhibidores de Proteínas Quinasas/administración & dosificación; Proteínas Tirosina Quinasas/antagonistas & inhibidores; Proteínas Proto-Oncogénicas/antagonistas & inhibidores; Pirazoles/farmacología; Piridinas/farmacología; Sulfonas/farmacología; Sindecano-4/genética; Triazinas/farmacología

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Tirosina Quinasas / Proteínas de Fusión Oncogénica / Proteínas Proto-Oncogénicas / Inhibidores de Proteínas Quinasas / Neoplasias Hepáticas Experimentales / Neoplasias Pulmonares Límite: Animals / Humans Idioma: En Revista: Carcinogenesis Año: 2016 Tipo del documento: Article

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