[The circadian system in man: From the internal clock to melatonin secretion]. / À propos du système circadien chez l'homme : de l'horloge interne à la sécrétion de mélatonine.
Ann Pharm Fr
; 74(5): 331-4, 2016 Sep.
Article
en Fr
| MEDLINE
| ID: mdl-26993958
ABSTRACT
The internal or biological clock which is located in the suprachiasmatic nuclei of the anterior hypothalamus is controlled by clock genes and environmental factors which are able to synchronize the clock to 24h. Rhythm desynchronization (shiftwork and nightwork, transmeridian flights, aging, some psychiatric diseases, blindness, intake of some drugs
) occurs when the internal clock does no longer work in harmony with the astronomical time i.e. our watch. The circadian system consists of three major elements, which are the clock, the retinohypothalamic tract and melatonin which is secreted by the pineal gland and considered as the arrow of the clock. Both light and melatonin present a phase response curve useful for the treatment of sleep circadian disorders.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Relojes Biológicos
/
Ritmo Circadiano
/
Melatonina
Límite:
Humans
Idioma:
Fr
Revista:
Ann Pharm Fr
Año:
2016
Tipo del documento:
Article