Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity.

Buland, Justin R; Wasserloos, Karla J; Tyurin, Vladimir A; Tyurina, Yulia Y; Amoscato, Andrew A; Mallampalli, Rama K; Chen, Bill B; Zhao, Jing; Zhao, Yutong; Ofori-Acquah, Solomon; Kagan, Valerian E; Pitt, Bruce R

Buland, Justin R; Wasserloos, Karla J; Tyurin, Vladimir A; Tyurina, Yulia Y; Amoscato, Andrew A; Mallampalli, Rama K; Chen, Bill B; Zhao, Jing; Zhao, Yutong; Ofori-Acquah, Solomon; Kagan, Valerian E; Pitt, Bruce R.

Afiliación

Buland JR; Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania; University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Vascular Medicine Institute, Pittsburgh, Pennsylvania;
Wasserloos KJ; University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania;
Tyurin VA; University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania;
Tyurina YY; University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania;
Amoscato AA; University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania;
Mallampalli RK; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Acute Lung Injury Center of Excellence, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; VA Pittsburgh Health Care System, P
Chen BB; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Acute Lung Injury Center of Excellence, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;
Zhao J; Vascular Medicine Institute, Pittsburgh, Pennsylvania; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Acute Lung Injury Center of Excellence, University of Pittsburgh School of Medicine, Pittsb
Zhao Y; University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Vascular Medicine Institute, Pittsburgh, Pennsylvania; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Acute Lung Injury Ce
Ofori-Acquah S; University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Vascular Medicine Institute, Pittsburgh, Pennsylvania;
Kagan VE; University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania;
Pitt BR; University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania; brucep@pitt.edu.

Am J Physiol Lung Cell Mol Physiol ; 311(2): L303-16, 2016 08 01.

Article en En | MEDLINE | ID: mdl-27233995

Asunto(s)

1-Alquil-2-acetilglicerofosfocolina Esterasa/fisiología; Cardiolipinas/biosíntesis; Células Endoteliales/fisiología; Animales; Cardiolipinas/sangre; Bovinos; Células Cultivadas; Impedancia Eléctrica; Hidrólisis; Ratones Endogámicos C57BL; Oxidación-Reducción; Infecciones por Pseudomonas/sangre; Transducción de Señal

Palabras clave

cardiolipin; lineolic acid; lipoprotein-associated phospholipase A2; octadecadienoic acid; pulmonary endothelium

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cardiolipinas / Células Endoteliales / 1-Alquil-2-acetilglicerofosfocolina Esterasa Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Asunto de la revista: BIOLOGIA MOLECULAR / FISIOLOGIA Año: 2016 Tipo del documento: Article

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