Deletion of Nrf2 leads to hepatic insulin resistance via the activation of NF-&#954;B in mice fed a high-fat diet.

Liu, Zhenxiong; Dou, Weijia; Ni, Zhen; Wen, Qinsheng; Zhang, Rong; Qin, Ming; Wang, Xuxia; Tang, Hua; Cao, Ying; Wang, Jingjie; Zhao, Shuguang

Deletion of Nrf2 leads to hepatic insulin resistance via the activation of NF-κB in mice fed a high-fat diet.

Liu, Zhenxiong; Dou, Weijia; Ni, Zhen; Wen, Qinsheng; Zhang, Rong; Qin, Ming; Wang, Xuxia; Tang, Hua; Cao, Ying; Wang, Jingjie; Zhao, Shuguang.

Afiliación

Liu Z; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
Dou W; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
Ni Z; Department of Digestion, General Hospital of Chengdu Military Command, Chengdu, Sichuan 610000, P.R. China.
Wen Q; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
Zhang R; Department of Gastroenterology, Xianyang Hospital of Yan'an University, Xianyang, Shaanxi 712000, P.R. China.
Qin M; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
Wang X; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
Tang H; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
Cao Y; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
Wang J; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
Zhao S; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.

Mol Med Rep ; 14(2): 1323-31, 2016 Aug.

Article en En | MEDLINE | ID: mdl-27315552

Asunto(s)

Dieta Alta en Grasa; Eliminación de Gen; Resistencia a la Insulina/genética; Hígado/metabolismo; Factor 2 Relacionado con NF-E2/deficiencia; FN-kappa B/metabolismo; Animales; Glucemia; Modelos Animales de Enfermedad; Glutatión/metabolismo; Peroxidación de Lípido; Hígado/patología; Masculino; Malondialdehído/metabolismo; Ratones; Ratones Noqueados; Factor 2 Relacionado con NF-E2/genética; Factor 2 Relacionado con NF-E2/metabolismo; Enfermedad del Hígado Graso no Alcohólico/etiología; Enfermedad del Hígado Graso no Alcohólico/metabolismo; Enfermedad del Hígado Graso no Alcohólico/patología; Estrés Oxidativo; Transducción de Señal

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Resistencia a la Insulina / FN-kappa B / Eliminación de Gen / Factor 2 Relacionado con NF-E2 / Dieta Alta en Grasa / Hígado Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Mol Med Rep Año: 2016 Tipo del documento: Article

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