IRGB10 Exposes Bacteria's Intimate Secrets.

Hoss, Florian; Budden, Christina F; Latz, Eicke

Hoss, Florian; Budden, Christina F; Latz, Eicke.

Afiliación

Hoss F; Institute of Innate Immunity, University Hospitals, University of Bonn, 53127 Bonn, Germany.
Budden CF; Institute of Innate Immunity, University Hospitals, University of Bonn, 53127 Bonn, Germany.
Latz E; Institute of Innate Immunity, University Hospitals, University of Bonn, 53127 Bonn, Germany; Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA 01655, USA. Electronic address: eicke.latz@uni-bonn.de.

Dev Cell ; 39(1): 7-8, 2016 10 10.

Article en En | MEDLINE | ID: mdl-27728782

ABSTRACT

ABSTRACT

When bacteria infect a cell, the bacterial membrane partially shields microbial structures from the immune system, preventing detection and clearance. In a recent issue of Cell, Man et al. (2016) show that the interferon-inducible protein IRGB10 liberates bacterial ligands for sensing by both the AIM2 and the non-canonical NLRP3 inflammasomes.

Asunto(s)

Bacterias/metabolismo; Inflamasomas/inmunología

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bacterias / Inflamasomas Idioma: En Revista: Dev Cell Asunto de la revista: EMBRIOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Alemania

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