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Validation and development of MTH1 inhibitors for treatment of cancer.
Warpman Berglund, U; Sanjiv, K; Gad, H; Kalderén, C; Koolmeister, T; Pham, T; Gokturk, C; Jafari, R; Maddalo, G; Seashore-Ludlow, B; Chernobrovkin, A; Manoilov, A; Pateras, I S; Rasti, A; Jemth, A-S; Almlöf, I; Loseva, O; Visnes, T; Einarsdottir, B O; Gaugaz, F Z; Saleh, A; Platzack, B; Wallner, O A; Vallin, K S A; Henriksson, M; Wakchaure, P; Borhade, S; Herr, P; Kallberg, Y; Baranczewski, P; Homan, E J; Wiita, E; Nagpal, V; Meijer, T; Schipper, N; Rudd, S G; Bräutigam, L; Lindqvist, A; Filppula, A; Lee, T-C; Artursson, P; Nilsson, J A; Gorgoulis, V G; Lehtiö, J; Zubarev, R A; Scobie, M; Helleday, T.
Afiliación
  • Warpman Berglund U; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Sanjiv K; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Gad H; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Kalderén C; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Koolmeister T; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Pham T; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Gokturk C; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Jafari R; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology.
  • Maddalo G; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology.
  • Seashore-Ludlow B; Chemical Biology Consortium Sweden, Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Chernobrovkin A; Division of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Manoilov A; Division of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Pateras IS; Molecular Carcinogenesis Group, Department of Histology and Embryology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • Rasti A; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Jemth AS; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Almlöf I; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Loseva O; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Visnes T; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Einarsdottir BO; Sahlgrenska Translational Melanoma Group (SATMEG), Sahlgrenska Cancer Center, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg.
  • Gaugaz FZ; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Saleh A; Department of Pharmacy and.
  • Platzack B; Science for Life Laboratory Drug Discovery and Development Platform, ADME of Therapeutics facility, Department of Phamracy, Uppsala University, Uppsala, Sweden.
  • Wallner OA; Swedish Toxicology Sciences Research Center, Södertälje, Sweden.
  • Vallin KS; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Henriksson M; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Wakchaure P; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Borhade S; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Herr P; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Kallberg Y; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Baranczewski P; National Bioinformatics Infrastructure Sweden (NBIS), Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet, Stockholm.
  • Homan EJ; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Wiita E; Science for Life Laboratory Drug Discovery and Development Platform, ADME of Therapeutics facility, Department of Phamracy, Uppsala University, Uppsala, Sweden.
  • Nagpal V; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Meijer T; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Schipper N; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Rudd SG; SP Process Development, Södertälje, Sweden.
  • Bräutigam L; SP Process Development, Södertälje, Sweden.
  • Lindqvist A; SP Process Development, Södertälje, Sweden.
  • Filppula A; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Lee TC; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics.
  • Artursson P; Science for Life Laboratory Drug Discovery and Development Platform, ADME of Therapeutics facility, Department of Phamracy, Uppsala University, Uppsala, Sweden.
  • Nilsson JA; Uppsala Drug Optimisation and Pharmaceutical Profiling Platform (UDOPP), Department of Pharmacy, Uppsala University, Uppsala, Sweden.
  • Gorgoulis VG; Institute of biomedical sciences, Academia Sinica, Taipei-115, Taiwan.
  • Lehtiö J; Department of Pharmacy and.
  • Zubarev RA; Science for Life Laboratory Drug Discovery and Development Platform, ADME of Therapeutics facility, Department of Phamracy, Uppsala University, Uppsala, Sweden.
  • Scobie M; Uppsala Drug Optimisation and Pharmaceutical Profiling Platform (UDOPP), Department of Pharmacy, Uppsala University, Uppsala, Sweden.
  • Helleday T; Sahlgrenska Translational Melanoma Group (SATMEG), Sahlgrenska Cancer Center, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg.
Ann Oncol ; 27(12): 2275-2283, 2016 12.
Article en En | MEDLINE | ID: mdl-27827301
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirimidinas / Monoéster Fosfórico Hidrolasas / Enzimas Reparadoras del ADN / Inhibidores Enzimáticos / Neoplasias Límite: Animals / Humans Idioma: En Revista: Ann Oncol Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirimidinas / Monoéster Fosfórico Hidrolasas / Enzimas Reparadoras del ADN / Inhibidores Enzimáticos / Neoplasias Límite: Animals / Humans Idioma: En Revista: Ann Oncol Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article