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Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates.
Staben, Leanna R; Koenig, Stefan G; Lehar, Sophie M; Vandlen, Richard; Zhang, Donglu; Chuh, Josefa; Yu, Shang-Fan; Ng, Carl; Guo, Jun; Liu, Yanzhou; Fourie-O'Donohue, Aimee; Go, MaryAnn; Linghu, Xin; Segraves, Nathaniel L; Wang, Tao; Chen, Jinhua; Wei, BinQing; Phillips, Gail D Lewis; Xu, Keyang; Kozak, Katherine R; Mariathasan, Sanjeev; Flygare, John A; Pillow, Thomas H.
Afiliación
  • Staben LR; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Koenig SG; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Lehar SM; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Vandlen R; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Zhang D; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Chuh J; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Yu SF; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Ng C; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Guo J; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Liu Y; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Fourie-O'Donohue A; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Go M; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Linghu X; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Segraves NL; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Wang T; WuXi AppTec Co., Ltd, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Chen J; WuXi AppTec Co., Ltd, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Wei B; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Phillips GD; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Xu K; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Kozak KR; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Mariathasan S; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Flygare JA; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
  • Pillow TH; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
Nat Chem ; 8(12): 1112-1119, 2016 12.
Article en En | MEDLINE | ID: mdl-27874860
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Portadores de Fármacos / Preparaciones Farmacéuticas / Inmunoconjugados / Aminas / Anticuerpos Monoclonales Límite: Humans Idioma: En Revista: Nat Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Portadores de Fármacos / Preparaciones Farmacéuticas / Inmunoconjugados / Aminas / Anticuerpos Monoclonales Límite: Humans Idioma: En Revista: Nat Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos