Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models.

Tan, Qiumin; Yalamanchili, Hari Krishna; Park, Jeehye; De Maio, Antonia; Lu, Hsiang-Chih; Wan, Ying-Wooi; White, Joshua J; Bondar, Vitaliy V; Sayegh, Layal S; Liu, Xiuyun; Gao, Yan; Sillitoe, Roy V; Orr, Harry T; Liu, Zhandong; Zoghbi, Huda Y

Tan, Qiumin; Yalamanchili, Hari Krishna; Park, Jeehye; De Maio, Antonia; Lu, Hsiang-Chih; Wan, Ying-Wooi; White, Joshua J; Bondar, Vitaliy V; Sayegh, Layal S; Liu, Xiuyun; Gao, Yan; Sillitoe, Roy V; Orr, Harry T; Liu, Zhandong; Zoghbi, Huda Y.

Afiliación

Tan Q; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
Yalamanchili HK; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, Texas 77030, USA.
Park J; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
De Maio A; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, Texas 77030, USA.
Lu HC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
Wan YW; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, Texas 77030, USA.
White JJ; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, Texas 77030, USA.
Bondar VV; Program in Developmental Biology.
Sayegh LS; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, Texas 77030, USA.
Liu X; Program in Developmental Biology.
Gao Y; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
Sillitoe RV; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, Texas 77030, USA.
Orr HT; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, Texas 77030, USA.
Liu Z; Department of Neuroscience.
Zoghbi HY; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.

Hum Mol Genet ; 25(23): 5083-5093, 2016 12 01.

Article en En | MEDLINE | ID: mdl-28007900

Asunto(s)

Esclerosis Amiotrófica Lateral/genética; Proteínas de Unión al ADN/genética; Demencia Frontotemporal/genética; Degeneración Nerviosa/genética; Proteínas del Tejido Nervioso/genética; Factores de Empalme de ARN/genética; Esclerosis Amiotrófica Lateral/fisiopatología; Animales; Biología Computacional/métodos; Modelos Animales de Enfermedad; Exones/genética; Demencia Frontotemporal/fisiopatología; Regulación del Desarrollo de la Expresión Génica; Humanos; Ratones; Degeneración Nerviosa/patología; Proteínas del Tejido Nervioso/biosíntesis; Células de Purkinje/metabolismo; Células de Purkinje/patología; Empalme del ARN/genética; Factores de Empalme de ARN/biosíntesis; Proteínas de Unión al ARN/biosíntesis; Proteínas de Unión al ARN/genética

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas de Unión al ADN / Demencia Frontotemporal / Factores de Empalme de ARN / Esclerosis Amiotrófica Lateral / Degeneración Nerviosa / Proteínas del Tejido Nervioso Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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