Blue Rubber Bleb Nevus Syndrome: Promising Response To Sirolimus.

ABSTRACT

BACKGROUND: Blue rubber bleb nevus syndrome is a rare disease involving venous malformations. CASE CHARACTERISTICS We present a 6-year-old female with the syndrome, and consumptive coagulopathy. INTERVENTION/OUTCOME: After management with sirolimus, symptoms resolved. MESSAGE Sirolimus may be a valuable option for reducing bleeding complications and cosmetic sequelae for the patients with this syndrome.