Poor sensitivity of rapid tests for the detection of antibodies to the hepatitis B virus: implications for field studies.
Mem Inst Oswaldo Cruz
; 112(3): 209-213, 2017 Mar.
Article
en En
| MEDLINE
| ID: mdl-28146158
ABSTRACT
Rapid tests (RTs) can be used as an alternative method for the conventional diagnosis of hepatitis B virus (HBV). This study aims to evaluate antibodies to HBsAg (anti-HBs) and antibodies to HBeAg (anti-HBe) RTs under different Brazilian settings. The following three groups were included GI viral hepatitis outpatient services; GII low resource areas; and GIII crack users and beauticians. Imuno-rápido anti-HBsAg™ and Imuno-rápido anti-HBeAg™ RTs were evaluated and showed specificities greater than 95% in all groups. The sensitivity values to anti-HBs were 50.38%, 51.05% and 46.73% and the sensitivity values to anti-HBe were 76.99%, 10.34% and 11.76% in the GI, GII and GIII groups, respectively. The assays had a low sensitivity and high specificity, which indicated their use for screening in regions endemic for HBV.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Virus de la Hepatitis B
/
Hepatitis B
/
Anticuerpos contra la Hepatitis B
/
Antígenos e de la Hepatitis B
/
Antígenos de Superficie de la Hepatitis B
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
/
Humans
/
Middle aged
Idioma:
En
Revista:
Mem Inst Oswaldo Cruz
Año:
2017
Tipo del documento:
Article
País de afiliación:
Brasil