MiR-23a-5p modulates mycobacterial survival and autophagy during mycobacterium tuberculosis infection through TLR2/MyD88/NF-&#954;B pathway by targeting TLR2.

Gu, Xing; Gao, Yan; Mu, De-Guang; Fu, En-Qing

MiR-23a-5p modulates mycobacterial survival and autophagy during mycobacterium tuberculosis infection through TLR2/MyD88/NF-κB pathway by targeting TLR2.

Gu, Xing; Gao, Yan; Mu, De-Guang; Fu, En-Qing.

Afiliación

Gu X; Respiratory and Critical Care Medicine, Tangdu Hospital, The Fourth Military Medical University, No. 1 Xinsi Road, Xi'an 710038, Shaanxi, PR China.
Gao Y; Department of Respiratory Medicine, People's Hospital of BaoJi City, Baoji 721000, Shaanxi, PR China.
Mu DG; Respiratory and Critical Care Medicine, Tangdu Hospital, The Fourth Military Medical University, No. 1 Xinsi Road, Xi'an 710038, Shaanxi, PR China. Electronic address: deguang@fmmu.edu.cn.
Fu EQ; Respiratory and Critical Care Medicine, Tangdu Hospital, The Fourth Military Medical University, No. 1 Xinsi Road, Xi'an 710038, Shaanxi, PR China. Electronic address: enqingfu66@163.com.

Exp Cell Res ; 354(2): 71-77, 2017 05 15.

Article en En | MEDLINE | ID: mdl-28327409

Asunto(s)

Autofagia/genética; MicroARNs/metabolismo; Viabilidad Microbiana; Mycobacterium tuberculosis/fisiología; Factor 88 de Diferenciación Mieloide/metabolismo; FN-kappa B/metabolismo; Receptor Toll-Like 2/metabolismo; Tuberculosis/genética; Regiones no Traducidas 3'/genética; Animales; Secuencia de Bases; Regulación de la Expresión Génica; Espacio Intracelular/microbiología; Macrófagos/metabolismo; Macrófagos/microbiología; Ratones; MicroARNs/genética; Unión Proteica/genética; Células RAW 264.7; Transducción de Señal; Receptor Toll-Like 2/genética; Tuberculosis/inmunología; Tuberculosis/microbiología; Tuberculosis/patología

Palabras clave

Autophagy; Mycobacterium tuberculosis (M.tb.); TLR2/MyD88/NF-κB pathway; miR-23a-5p

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autofagia / Tuberculosis / FN-kappa B / MicroARNs / Receptor Toll-Like 2 / Viabilidad Microbiana / Factor 88 de Diferenciación Mieloide / Mycobacterium tuberculosis Límite: Animals Idioma: En Revista: Exp Cell Res Año: 2017 Tipo del documento: Article

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