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Residual hormone levels in used contraceptive rings as a measurement of adherence to vaginal ring use.
Haaland, Richard E; Holder, Angela; Evans-Strickfaden, Tammy; Nyagol, Beatrice; Makanga, Mumbi; Oyaro, Boaz; Humwa, Felix; Williams, Tiffany; McLellan-Lemal, Eleanor; Desai, Mitesh; Huey, Michael J.
Afiliación
  • Haaland RE; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA, USA 30329. Electronic address: hyw9@cdc.gov.
  • Holder A; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA, USA 30329. Electronic address: fka5@cdc.gov.
  • Evans-Strickfaden T; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA, USA 30329. Electronic address: tae0@cdc.gov.
  • Nyagol B; KEMRI/CDC Research Field Station, P.O. Box 1578, Kisumu, Kenya. Electronic address: Bnyagol@kemricdc.org.
  • Makanga M; KEMRI/CDC Research Field Station, P.O. Box 1578, Kisumu, Kenya. Electronic address: mmakanga@kemricdc.org.
  • Oyaro B; KEMRI/CDC Research Field Station, P.O. Box 1578, Kisumu, Kenya. Electronic address: Boyaro@kemricdc.org.
  • Humwa F; KEMRI/CDC Research Field Station, P.O. Box 1578, Kisumu, Kenya. Electronic address: FHumwa@kemricdc.org.
  • Williams T; ICF International, Assigned to Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA 30329. Electronic address: wuq0@cdc.gov.
  • McLellan-Lemal E; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA, USA 30329. Electronic address: egm4@cdc.gov.
  • Desai M; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA, USA 30329. Electronic address: gdo5@cdc.gov.
  • Huey MJ; Emory University Student Health Services, Emory University School of Medicine, 1525 Clifton Road, Atlanta, GA, USA 30322. Electronic address: mhuey@emory.edu.
Contraception ; 95(6): 602-604, 2017 Jun.
Article en En | MEDLINE | ID: mdl-28372978
ABSTRACT

OBJECTIVE:

This study sought to measure residual contraceptive hormone levels in vaginal rings as an adherence marker for monitoring product use in clinical trials. STUDY

DESIGN:

Residual etonogestrel and ethinyl estradiol levels from used NuvaRings® of 26 self-reported adherent women enrolled in a clinical trial of vaginal ring acceptability were compared to those from 16 women who used NuvaRing® as their contraceptive choice.

RESULTS:

Twenty-one (81%) clinical trial rings had contraceptive hormone levels within the range of those used as a contraceptive choice. Five returned rings had unused or discordant levels of residual contraceptive hormones.

CONCLUSION:

Residual vaginal ring drug levels could help assess adherence in clinical trials.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cooperación del Paciente / Desogestrel / Anticonceptivos Femeninos / Dispositivos Anticonceptivos Femeninos / Etinilestradiol Límite: Female / Humans País/Región como asunto: Africa / America do norte Idioma: En Revista: Contraception Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cooperación del Paciente / Desogestrel / Anticonceptivos Femeninos / Dispositivos Anticonceptivos Femeninos / Etinilestradiol Límite: Female / Humans País/Región como asunto: Africa / America do norte Idioma: En Revista: Contraception Año: 2017 Tipo del documento: Article