Related GPCRs couple differently to Gs: preassociation between G protein and 5-HT7 serotonin receptor reveals movement of G&#945;s upon receptor activation.

Andressen, Kjetil Wessel; Ulsund, Andrea Hembre; Krobert, Kurt A; Lohse, Martin J; Bünemann, Moritz; Levy, Finn Olav

Related GPCRs couple differently to G_s: preassociation between G protein and 5-HT₇ serotonin receptor reveals movement of Gα_s upon receptor activation.

Andressen, Kjetil Wessel; Ulsund, Andrea Hembre; Krobert, Kurt A; Lohse, Martin J; Bünemann, Moritz; Levy, Finn Olav.

Afiliación

Andressen KW; Department of Pharmacology, Institute of Clinical Medicine, Oslo University Hospital, University of Oslo, Oslo, Norway.
Ulsund AH; Center for Heart Failure Research, Faculty of Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway.
Krobert KA; Department of Pharmacology, Institute of Clinical Medicine, Oslo University Hospital, University of Oslo, Oslo, Norway.
Lohse MJ; Center for Heart Failure Research, Faculty of Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway.
Bünemann M; Department of Pharmacology, Institute of Clinical Medicine, Oslo University Hospital, University of Oslo, Oslo, Norway.
Levy FO; Center for Heart Failure Research, Faculty of Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway.

FASEB J ; 32(2): 1059-1069, 2018 02.

Article en En | MEDLINE | ID: mdl-29079700

Asunto(s)

Cromograninas/metabolismo; Subunidades alfa de la Proteína de Unión al GTP Gs/metabolismo; Receptores de Serotonina/metabolismo; Cromograninas/genética; Subunidades alfa de la Proteína de Unión al GTP Gs/genética; Subunidades beta de la Proteína de Unión al GTP/genética; Subunidades beta de la Proteína de Unión al GTP/metabolismo; Subunidades gamma de la Proteína de Unión al GTP/genética; Subunidades gamma de la Proteína de Unión al GTP/metabolismo; Células HEK293; Humanos; Receptores de Serotonina/genética; Receptores de Serotonina 5-HT4/genética; Receptores de Serotonina 5-HT4/metabolismo

Palabras clave

FRAP; FRET; Gnas; collision coupling; precoupling

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cromograninas / Receptores de Serotonina / Subunidades alfa de la Proteína de Unión al GTP Gs Límite: Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Noruega

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