Out of Southern East Asia of the Brown Rat Revealed by Large-Scale Genome Sequencing.
Mol Biol Evol
; 35(1): 149-158, 2018 01 01.
Article
en En
| MEDLINE
| ID: mdl-29087519
ABSTRACT
The geographic origin and migration of the brown rat (Rattus norvegicus) remain subjects of considerable debate. In this study, we sequenced whole genomes of 110 wild brown rats with a diverse world-wide representation. We reveal that brown rats migrated out of southern East Asia, rather than northern Asia as formerly suggested, into the Middle East and then to Europe and Africa, thousands of years ago. Comparison of genomes from different geographical populations reveals that many genes involved in the immune system experienced positive selection in the wild brown rat.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Ratas
/
Filogeografía
Límite:
Animals
País/Región como asunto:
Africa
/
Asia
/
Europa
Idioma:
En
Revista:
Mol Biol Evol
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2018
Tipo del documento:
Article
País de afiliación:
China