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First-in-Human Study With the Inhaled TLR9 Oligonucleotide Agonist AZD1419 Results in Interferon Responses in the Lung, and Is Safe and Well-Tolerated.
Jackson, Sam; Candia, Albert F; Delaney, Stephen; Floettmann, Simone; Wong, Clifford; Campbell, John D; Kell, Sariah; Lum, Jeremy; Hessel, Edith M; Traquina, Paula; McHale, Mark; Robinson, Ian; Bell, John; Fuhr, Rainard; Keeling, David; Coffman, Robert L.
Afiliación
  • Jackson S; Dynavax Technologies, Berkeley, California, USA.
  • Candia AF; Dynavax Technologies, Berkeley, California, USA.
  • Delaney S; Respiratory, Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Floettmann S; PAREXEL International GmbH, Berlin, Germany.
  • Wong C; Dynavax Technologies, Berkeley, California, USA.
  • Campbell JD; Dynavax Technologies, Berkeley, California, USA.
  • Kell S; Dynavax Technologies, Berkeley, California, USA.
  • Lum J; Dynavax Technologies, Berkeley, California, USA.
  • Hessel EM; Dynavax Technologies, Berkeley, California, USA.
  • Traquina P; Dynavax Technologies, Berkeley, California, USA.
  • McHale M; Respiratory, Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Robinson I; Respiratory, Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Bell J; Respiratory, Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Fuhr R; PAREXEL International GmbH, Berlin, Germany.
  • Keeling D; Respiratory, Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Coffman RL; Dynavax Technologies, Berkeley, California, USA.
Clin Pharmacol Ther ; 104(2): 335-345, 2018 08.
Article en En | MEDLINE | ID: mdl-29134633
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oligonucleótidos / Interferón Tipo I / Células Th2 / Antiasmáticos / Receptor Toll-Like 9 / Pulmón Tipo de estudio: Clinical_trials / Etiology_studies / Risk_factors_studies Límite: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Pharmacol Ther Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oligonucleótidos / Interferón Tipo I / Células Th2 / Antiasmáticos / Receptor Toll-Like 9 / Pulmón Tipo de estudio: Clinical_trials / Etiology_studies / Risk_factors_studies Límite: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Pharmacol Ther Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos