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From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection.
Kudalkar, Shalley N; Beloor, Jagadish; Quijano, Elias; Spasov, Krasimir A; Lee, Won-Gil; Cisneros, José A; Saltzman, W Mark; Kumar, Priti; Jorgensen, William L; Anderson, Karen S.
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  • Kudalkar SN; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520-8066.
  • Beloor J; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06520-8066.
  • Quijano E; Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT 06520.
  • Spasov KA; Department of Biomedical Engineering, Yale University, New Haven, CT 06511.
  • Lee WG; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520-8066.
  • Cisneros JA; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06520-8066.
  • Saltzman WM; Department of Chemistry, Yale University, New Haven, CT 06520-8107.
  • Kumar P; Department of Chemistry, Yale University, New Haven, CT 06520-8107.
  • Jorgensen WL; Department of Biomedical Engineering, Yale University, New Haven, CT 06511; mark.saltzman@yale.edu priti.kumar@yale.edu william.jorgensen@yale.edu karen.anderson@yale.edu.
  • Anderson KS; Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT 06520; mark.saltzman@yale.edu priti.kumar@yale.edu william.jorgensen@yale.edu karen.anderson@yale.edu.
Proc Natl Acad Sci U S A ; 115(4): E802-E811, 2018 01 23.
Article en En | MEDLINE | ID: mdl-29279368
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 / Sistemas de Liberación de Medicamentos / Fármacos Anti-VIH Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 / Sistemas de Liberación de Medicamentos / Fármacos Anti-VIH Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article