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Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling.
Richter, Melanie; Murtaza, Nadeem; Scharrenberg, Robin; White, Sean H; Johanns, Ole; Walker, Susan; Yuen, Ryan K C; Schwanke, Birgit; Bedürftig, Bianca; Henis, Melad; Scharf, Sarah; Kraus, Vanessa; Dörk, Ronja; Hellmann, Jakob; Lindenmaier, Zsuzsa; Ellegood, Jacob; Hartung, Henrike; Kwan, Vickie; Sedlacik, Jan; Fiehler, Jens; Schweizer, Michaela; Lerch, Jason P; Hanganu-Opatz, Ileana L; Morellini, Fabio; Scherer, Stephen W; Singh, Karun K; Calderon de Anda, Froylan.
Afiliación
  • Richter M; Center for Molecular Neurobiology Hamburg (ZMNH), Research Group Neuronal Development, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Murtaza N; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, Ontario, Canada.
  • Scharrenberg R; Department of Biochemistry and Biomedical Sciences, Michael G. DeGroote School of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
  • White SH; Center for Molecular Neurobiology Hamburg (ZMNH), Research Group Neuronal Development, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Johanns O; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, Ontario, Canada.
  • Walker S; Department of Biochemistry and Biomedical Sciences, Michael G. DeGroote School of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Yuen RKC; Center for Molecular Neurobiology Hamburg (ZMNH), Research Group Neuronal Development, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Schwanke B; The Centre for Applied Genomics and Program in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Bedürftig B; Department of Molecular Genetics and McLaughlin Centre, University of Toronto, Toronto, Ontario, Canada.
  • Henis M; The Centre for Applied Genomics and Program in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Scharf S; Department of Molecular Genetics and McLaughlin Centre, University of Toronto, Toronto, Ontario, Canada.
  • Kraus V; Center for Molecular Neurobiology Hamburg (ZMNH), Research Group Neuronal Development, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Dörk R; Center for Molecular Neurobiology Hamburg (ZMNH), Research Group Neuronal Development, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Hellmann J; Center for Molecular Neurobiology Hamburg (ZMNH), Research Group Neuronal Development, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Lindenmaier Z; Department of Anatomy and Histology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
  • Ellegood J; Center for Molecular Neurobiology Hamburg (ZMNH), Research Group Behavioral Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Hartung H; Center for Molecular Neurobiology Hamburg (ZMNH), Research Group Behavioral Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Kwan V; Center for Molecular Neurobiology Hamburg (ZMNH), Research Group Behavioral Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Sedlacik J; Center for Molecular Neurobiology Hamburg (ZMNH), Research Group Behavioral Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Fiehler J; Mouse Imaging Center, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Schweizer M; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • Lerch JP; Mouse Imaging Center, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Hanganu-Opatz IL; Developmental Neurophysiology, Institute of Neuroanatomy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Morellini F; Laboratory of Neurobiology, Department of Biosciences, University of Helsinki, Helsinki, Finland.
  • Scherer SW; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, Ontario, Canada.
  • Singh KK; Department of Biochemistry and Biomedical Sciences, Michael G. DeGroote School of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Calderon de Anda F; Department of Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Mol Psychiatry ; 24(9): 1329-1350, 2019 09.
Article en En | MEDLINE | ID: mdl-29467497
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Serina-Treonina Quinasas / Proteína de Unión al GTP rhoA / Trastornos del Neurodesarrollo / Trastorno del Espectro Autista Tipo de estudio: Etiology_studies Límite: Adult / Animals / Child / Female / Humans / Male Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2019 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Serina-Treonina Quinasas / Proteína de Unión al GTP rhoA / Trastornos del Neurodesarrollo / Trastorno del Espectro Autista Tipo de estudio: Etiology_studies Límite: Adult / Animals / Child / Female / Humans / Male Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2019 Tipo del documento: Article País de afiliación: Alemania