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The effects of angiotensin receptor neprilysin inhibition by sacubitril/valsartan on adipose tissue transcriptome and protein expression in obese hypertensive patients.
Stinkens, R; van der Kolk, B W; Jordan, J; Jax, T; Engeli, S; Heise, T; Jocken, J W; May, M; Schindler, C; Havekes, B; Schaper, N; Albrecht, D; Kaiser, S; Hartmann, N; Letzkus, M; Langenickel, T H; Goossens, G H; Blaak, E E.
Afiliación
  • Stinkens R; Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.
  • van der Kolk BW; Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.
  • Jordan J; Institute of Clinical Pharmacology, Hannover Medical School, Hannover, Germany.
  • Jax T; Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.
  • Engeli S; Profil GmbH, Neuss, Germany.
  • Heise T; Institute of Clinical Pharmacology, Hannover Medical School, Hannover, Germany.
  • Jocken JW; Profil GmbH, Neuss, Germany.
  • May M; Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.
  • Schindler C; Clinical Research Center Hannover, Hannover Medical School, Hannover, Germany.
  • Havekes B; Clinical Research Center Hannover, Hannover Medical School, Hannover, Germany.
  • Schaper N; Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands.
  • Albrecht D; Department of Internal Medicine, Division of Endocrinology, Maastricht University Medical Center+, Maastricht, The Netherlands.
  • Kaiser S; Department of Internal Medicine, Division of Endocrinology, Maastricht University Medical Center+, Maastricht, The Netherlands.
  • Hartmann N; CARIM School for Cardiovascular Diseases, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Center+, Maastricht, The Netherlands.
  • Letzkus M; Translational Medicine, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Langenickel TH; Translational Medicine, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Goossens GH; Translational Medicine, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Blaak EE; Translational Medicine, Novartis Institutes for Biomedical Research, Basel, Switzerland.
Sci Rep ; 8(1): 3933, 2018 03 02.
Article en En | MEDLINE | ID: mdl-29500454
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tetrazoles / Neprilisina / Proteínas / Tejido Adiposo / Antagonistas de Receptores de Angiotensina / Transcriptoma / Aminobutiratos / Hipertensión / Obesidad Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tetrazoles / Neprilisina / Proteínas / Tejido Adiposo / Antagonistas de Receptores de Angiotensina / Transcriptoma / Aminobutiratos / Hipertensión / Obesidad Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos