Tumor-on-a-chip platforms for assessing nanoparticle-based cancer therapy.
Nanotechnology
; 29(33): 332001, 2018 Aug 17.
Article
en En
| MEDLINE
| ID: mdl-29794338
ABSTRACT
Cancer has become the most prevalent cause of deaths, placing a huge economic and healthcare burden worldwide. Nanoparticles (NPs), as a key component of nanomedicine, provide alternative options for promoting the efficacy of cancer therapy. Current conventional cancer models have limitations in predicting the effects of various cancer treatments. To overcome these limitations, biomimetic and novel 'tumor-on-a-chip' platforms have emerged with other innovative biomedical engineering methods that enable the evaluation of NP-based cancer therapy. In this review, we first describe cancer models for evaluation of NP-based cancer therapy techniques, and then present the latest advances in 'tumor-on-a-chip' platforms that can potentially facilitate clinical translation of NP-based cancer therapies.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Ingeniería Biomédica
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Nanomedicina
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Nanopartículas
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Dispositivos Laboratorio en un Chip
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Modelos Biológicos
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Neoplasias
Tipo de estudio:
Prognostic_studies
Límite:
Animals
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Humans
Idioma:
En
Revista:
Nanotechnology
Año:
2018
Tipo del documento:
Article