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Design, selection and optimization of an anti-TRAIL-R2/anti-CD3 bispecific antibody able to educate T cells to recognize and destroy cancer cells.
Satta, Alessandro; Mezzanzanica, Delia; Caroli, Francesco; Frigerio, Barbara; Di Nicola, Massimo; Kontermann, Roland E; Iacovelli, Federico; Desideri, Alessandro; Anichini, Andrea; Canevari, Silvana; Gianni, Alessandro Massimo; Figini, Mariangela.
Afiliación
  • Satta A; a Molecular Therapies Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Mezzanzanica D; a Molecular Therapies Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Caroli F; a Molecular Therapies Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Frigerio B; a Molecular Therapies Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Di Nicola M; b Medical Oncology C Unit, Department of Medical Oncology and Hematology , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Kontermann RE; c Institut for Zellbiologie und Immunologie, Universität Stuttgart , Stuttgart , Germany.
  • Iacovelli F; d Department of Biology , University of Rome Tor Vergata , Rome , Italy.
  • Desideri A; d Department of Biology , University of Rome Tor Vergata , Rome , Italy.
  • Anichini A; e Human Tumor Immunobiology Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Canevari S; a Molecular Therapies Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Gianni AM; b Medical Oncology C Unit, Department of Medical Oncology and Hematology , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Figini M; f Department of Pathophysiology and Transplantation , University of Milan , Milan , Italy.
MAbs ; 10(7): 1084-1097, 2018 10.
Article en En | MEDLINE | ID: mdl-29993310
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T / Anticuerpos Biespecíficos / Anticuerpos de Cadena Única / Inmunoterapia / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T / Anticuerpos Biespecíficos / Anticuerpos de Cadena Única / Inmunoterapia / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Italia