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Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug.
Conklin, Laurie S; Damsker, Jesse M; Hoffman, Eric P; Jusko, William J; Mavroudis, Panteleimon D; Schwartz, Benjamin D; Mengle-Gaw, Laurel J; Smith, Edward C; Mah, Jean K; Guglieri, Michela; Nevo, Yoram; Kuntz, Nancy; McDonald, Craig M; Tulinius, Mar; Ryan, Monique M; Webster, Richard; Castro, Diana; Finkel, Richard S; Smith, Andrea L; Morgenroth, Lauren P; Arrieta, Adrienne; Shimony, Maya; Jaros, Mark; Shale, Phil; McCall, John M; Hathout, Yetrib; Nagaraju, Kanneboyina; van den Anker, John; Ward, Leanne M; Ahmet, Alexandra; Cornish, Michaelyn R; Clemens, Paula R.
Afiliación
  • Conklin LS; ReveraGen Biopharma, LLC, Rockville, MD, USA; Children's National Health System, George Washington University, Washington, DC, USA.
  • Damsker JM; ReveraGen Biopharma, LLC, Rockville, MD, USA.
  • Hoffman EP; ReveraGen Biopharma, LLC, Rockville, MD, USA; Binghamton University- SUNY, Binghamton, NY, USA.
  • Jusko WJ; State University of New York-Buffalo, Buffalo, NY, USA.
  • Mavroudis PD; State University of New York-Buffalo, Buffalo, NY, USA.
  • Schwartz BD; Camden Group, LLC, St. Louis, MO, USA.
  • Mengle-Gaw LJ; Camden Group, LLC, St. Louis, MO, USA.
  • Smith EC; Duke University, Durham, NC, USA.
  • Mah JK; University of Calgary, Alberta Children's Hospital, Calgary, Alberta, Canada.
  • Guglieri M; Newcastle University, Newcastle, UK.
  • Nevo Y; Schneider Children's Medical Center of Israel, Tel Aviv University, Tel Aviv, Israel.
  • Kuntz N; Ann & Robert H. Lurie Children's Hospital Chicago, IL, USA.
  • McDonald CM; University of California Davis, Davis, CA, USA.
  • Tulinius M; Queen Silvia Children's Hospital, Gothenburg, Sweden.
  • Ryan MM; Royal Children's Hospital, University of Melbourne, Melbourne, Australia.
  • Webster R; The Children's Hospital at Westmead, Sydney, Australia.
  • Castro D; University of Texas Southwestern, Dallas, TX, USA.
  • Finkel RS; Nemours Children's Hospital, Orlando, FL, USA.
  • Smith AL; TRiNDS LLC, Kensington, MD, USA.
  • Morgenroth LP; TRiNDS LLC, Kensington, MD, USA.
  • Arrieta A; TRiNDS LLC, Kensington, MD, USA.
  • Shimony M; TRiNDS LLC, Kensington, MD, USA.
  • Jaros M; Summit Analytical, Denver, CO, USA.
  • Shale P; Summit Analytical, Denver, CO, USA.
  • McCall JM; ReveraGen Biopharma, LLC, Rockville, MD, USA.
  • Hathout Y; Binghamton University- SUNY, Binghamton, NY, USA.
  • Nagaraju K; ReveraGen Biopharma, LLC, Rockville, MD, USA; Binghamton University- SUNY, Binghamton, NY, USA.
  • van den Anker J; ReveraGen Biopharma, LLC, Rockville, MD, USA; Children's National Health System, George Washington University, Washington, DC, USA.
  • Ward LM; Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.
  • Ahmet A; Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.
  • Cornish MR; ReveraGen Biopharma, LLC, Rockville, MD, USA.
  • Clemens PR; University of Pittsburgh and Department of Veterans Affairs Medical Center, Pittsburgh, PA, USA. Electronic address: clempr@upmc.edu.
Pharmacol Res ; 136: 140-150, 2018 10.
Article en En | MEDLINE | ID: mdl-30219580
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pregnadienodioles / Distrofia Muscular de Duchenne / Antiinflamatorios Tipo de estudio: Clinical_trials Límite: Child / Child, preschool / Humans / Male Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pregnadienodioles / Distrofia Muscular de Duchenne / Antiinflamatorios Tipo de estudio: Clinical_trials Límite: Child / Child, preschool / Humans / Male Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos