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Antibiotic consumption in Germany: first data of a newly implemented web-based tool for local and national surveillance.
Schweickert, Birgitta; Feig, Marcel; Schneider, Marc; Willrich, Niklas; Behnke, Michael; Peña Diaz, Luis Alberto; Gastmeier, Petra; Richter, Doreen; Blank, Hans-Peter; Eckmanns, Tim; Abu Sin, Muna.
Afiliación
  • Schweickert B; Department of Nosocomial Infections, Surveillance of Antibiotic Resistance and Antibiotic Consumption, Robert Koch Institute, Seestr. 10, D-13353 Berlin, Germany.
  • Feig M; Department of Nosocomial Infections, Surveillance of Antibiotic Resistance and Antibiotic Consumption, Robert Koch Institute, Seestr. 10, D-13353 Berlin, Germany.
  • Schneider M; Department of Nosocomial Infections, Surveillance of Antibiotic Resistance and Antibiotic Consumption, Robert Koch Institute, Seestr. 10, D-13353 Berlin, Germany.
  • Willrich N; Department of Nosocomial Infections, Surveillance of Antibiotic Resistance and Antibiotic Consumption, Robert Koch Institute, Seestr. 10, D-13353 Berlin, Germany.
  • Behnke M; Institute for Hygiene and Environmental Medicine, Charité - University Medicine Berlin, Hindenburgdamm 27, D-12203 Berlin, Germany.
  • Peña Diaz LA; Institute for Hygiene and Environmental Medicine, Charité - University Medicine Berlin, Hindenburgdamm 27, D-12203 Berlin, Germany.
  • Gastmeier P; Institute for Hygiene and Environmental Medicine, Charité - University Medicine Berlin, Hindenburgdamm 27, D-12203 Berlin, Germany.
  • Richter D; Department of Nosocomial Infections, Surveillance of Antibiotic Resistance and Antibiotic Consumption, Robert Koch Institute, Seestr. 10, D-13353 Berlin, Germany.
  • Blank HP; Department of Nosocomial Infections, Surveillance of Antibiotic Resistance and Antibiotic Consumption, Robert Koch Institute, Seestr. 10, D-13353 Berlin, Germany.
  • Eckmanns T; Department of Nosocomial Infections, Surveillance of Antibiotic Resistance and Antibiotic Consumption, Robert Koch Institute, Seestr. 10, D-13353 Berlin, Germany.
  • Abu Sin M; Department of Nosocomial Infections, Surveillance of Antibiotic Resistance and Antibiotic Consumption, Robert Koch Institute, Seestr. 10, D-13353 Berlin, Germany.
J Antimicrob Chemother ; 73(12): 3505-3515, 2018 12 01.
Article en En | MEDLINE | ID: mdl-30239728
Objectives: The features of a newly established, web-based surveillance system for hospital antibiotic consumption are described and data on broad-spectrum antibiotic use in German acute care hospitals are presented. Methods: The watch- and reserve-group antibiotics, two categories of antibiotics derived from the WHO Essential Medicines List comprising key agents for antimicrobial stewardship, were used as a framework for data analysis. The median antibiotic consumption densities (ACDs; DDD/100 patient days) for the years 2015/16 based on data from 137 acute care hospitals have been calculated for whole facilities, ICUs and medical and surgical departments, stratified by type of care. Results: The new web-based system provides real-time surveillance at unit and facility levels, accessible to all relevant stakeholders. User-defined reports are available via an interactive database, various report types support different approaches to analysis, and different complementing quantification measures of antimicrobial consumption are available. Watch- and reserve-group antibiotics accounted for 42% and 2% of total antibiotic use, respectively. Surgical services presented with considerably lower median ACDs of the watch-group antibiotics compared with medical services. Tertiary care hospitals exhibited higher ACDs of the reserve-group antibiotics and carbapenems than primary/secondary care hospitals, while the ACDs of the watch-group antibiotics as a whole did not differ significantly. Comparing the proportional use with other European countries revealed a relatively high use of the watch-group, ranking beyond the 75th percentile. Conclusions: Because of its particular features the new web-based surveillance system is a valuable tool for antimicrobial stewardship. The WHO categories of watch- and reserve-group antibiotics proved to be a useful framework for the analysis of hospital antibiotic consumption data.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Recolección de Datos / Internet / Utilización de Medicamentos / Antibacterianos Tipo de estudio: Evaluation_studies / Screening_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: J Antimicrob Chemother Año: 2018 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Recolección de Datos / Internet / Utilización de Medicamentos / Antibacterianos Tipo de estudio: Evaluation_studies / Screening_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: J Antimicrob Chemother Año: 2018 Tipo del documento: Article País de afiliación: Alemania