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CZ-7, a new derivative of Claulansine F, ameliorates 2VO-induced vascular dementia in rats through a Nrf2-mediated antioxidant responses.
Liu, Dan-Dan; Yuan, Xia; Chu, Shi-Feng; Chen, Chen; Ren, Qian; Luo, Piao; Lin, Mei-Yu; Wang, Sha-Sha; Zhu, Tian-Bi; Ai, Qi-di; Zang, Ying-da; Zhang, Dong-Ming; He, Xin; Huang, Zhi-Hua; Sun, Hong-Shuo; Feng, Zhong-Ping; Chen, Nai-Hong.
Afiliación
  • Liu DD; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Yuan X; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
  • Chu SF; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Chen C; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Ren Q; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Luo P; Hunan University of Chinese Medicine, Changsha, 410208, China.
  • Lin MY; Hunan University of Chinese Medicine, Changsha, 410208, China.
  • Wang SS; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Zhu TB; Hunan University of Chinese Medicine, Changsha, 410208, China.
  • Ai QD; Hunan University of Chinese Medicine, Changsha, 410208, China.
  • Zang YD; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • Zhang DM; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
  • He X; Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
  • Huang ZH; University of Toronto, Toronto, ON, M5S 1A8, Canada.
  • Sun HS; University of Toronto, Toronto, ON, M5S 1A8, Canada.
  • Feng ZP; University of Toronto, Toronto, ON, M5S 1A8, Canada.
  • Chen NH; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. chennh@imm.ac.cn.
Acta Pharmacol Sin ; 40(4): 425-440, 2019 Apr.
Article en En | MEDLINE | ID: mdl-30382185
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Demencia Vascular / Arteria Carótida Común / Factor 2 Relacionado con NF-E2 / Antioxidantes Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Demencia Vascular / Arteria Carótida Común / Factor 2 Relacionado con NF-E2 / Antioxidantes Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China