Improved mitochondrial targeting effect of HPMA copolymer by SS20 peptide mediation and nonendocytosis pathway.

Liu, Yanxi; Li, Qiuyi; Xiong, Xiaofeng; Zhou, Zhou

Liu, Yanxi; Li, Qiuyi; Xiong, Xiaofeng; Zhou, Zhou.

Afiliación

Liu Y; Key Laboratory of Drug Targeting and Drug Delivery System of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China.
Li Q; Key Laboratory of Drug Targeting and Drug Delivery System of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China.
Xiong X; Key Laboratory of Drug Targeting and Drug Delivery System of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China.
Zhou Z; Key Laboratory of Drug Targeting and Drug Delivery System of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China.

J Pept Sci ; 25(2): e3144, 2019 Feb.

Article en En | MEDLINE | ID: mdl-30588703

Asunto(s)

Endocitosis; Metacrilatos/farmacocinética; Mitocondrias/metabolismo; Péptidos/farmacocinética; Polímeros/farmacocinética; Animales; Células Cultivadas; Endocitosis/efectos de los fármacos; Células HeLa; Humanos; Metacrilatos/síntesis química; Metacrilatos/química; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Mitocondrias/efectos de los fármacos; Péptidos/química; Polímeros/síntesis química; Polímeros/química; Células RAW 264.7; Distribución Tisular

Palabras clave

HPMA copolymer; SS20 peptide; mitochondrial targeting; nonendocytosis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptidos / Polímeros / Endocitosis / Metacrilatos / Mitocondrias Límite: Animals / Humans Idioma: En Revista: J Pept Sci Asunto de la revista: BIOQUIMICA Año: 2019 Tipo del documento: Article País de afiliación: China

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