Global Analysis of Genes Essential for Francisella tularensis Schu S4 Growth <i>In Vitro</i> and for Fitness during Competitive Infection of Fischer 344 Rats.

Ireland, Philip M; Bullifent, Helen L; Senior, Nicola J; Southern, Stephanie J; Yang, Zheng Rong; Ireland, Rachel E; Nelson, Michelle; Atkins, Helen S; Titball, Richard W; Scott, Andrew E

Global Analysis of Genes Essential for Francisella tularensis Schu S4 Growth In Vitro and for Fitness during Competitive Infection of Fischer 344 Rats.

Ireland, Philip M; Bullifent, Helen L; Senior, Nicola J; Southern, Stephanie J; Yang, Zheng Rong; Ireland, Rachel E; Nelson, Michelle; Atkins, Helen S; Titball, Richard W; Scott, Andrew E.

Afiliación

Ireland PM; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom pmireland@dstl.gov.uk.
Bullifent HL; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
Senior NJ; College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Southern SJ; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
Yang ZR; College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Ireland RE; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
Nelson M; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
Atkins HS; Defence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
Titball RW; College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Scott AE; Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.

J Bacteriol ; 201(7)2019 04 01.

Article en En | MEDLINE | ID: mdl-30642993

Asunto(s)

Francisella tularensis/crecimiento & desarrollo; Francisella tularensis/genética; Genes Bacterianos; Tularemia/microbiología; Factores de Virulencia/genética; Animales; Análisis Mutacional de ADN; Elementos Transponibles de ADN; Modelos Animales de Enfermedad; Pruebas Genéticas; Mutagénesis Insercional; Neocallimastigales; Ratas Endogámicas F344

Palabras clave

Francisella; TraDIS; essential genes; gene essentiality; genomics; transposon insertion sequencing; virulence

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tularemia / Factores de Virulencia / Francisella tularensis / Genes Bacterianos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Bacteriol Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido

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