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Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque.
Espinoza, Diego A; Fan, Xing; Yang, Di; Cordes, Stefan F; Truitt, Lauren L; Calvo, Katherine R; Yabe, Idalia M; Demirci, Selami; Hope, Kristin J; Hong, So Gun; Krouse, Allen; Metzger, Mark; Bonifacino, Aylin; Lu, Rong; Uchida, Naoya; Tisdale, John F; Wu, Xiaolin; DeRavin, Suk See; Malech, Harry L; Donahue, Robert E; Wu, Chuanfeng; Dunbar, Cynthia E.
Afiliación
  • Espinoza DA; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Fan X; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA.
  • Yang D; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Cordes SF; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA.
  • Truitt LL; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA.
  • Calvo KR; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA.
  • Yabe IM; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA.
  • Demirci S; Sickle Cell and Vascular Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
  • Hope KJ; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, Canada.
  • Hong SG; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA.
  • Krouse A; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA.
  • Metzger M; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA.
  • Bonifacino A; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA.
  • Lu R; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, USA.
  • Uchida N; Sickle Cell and Vascular Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
  • Tisdale JF; Sickle Cell and Vascular Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
  • Wu X; Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • DeRavin SS; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.
  • Malech HL; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.
  • Donahue RE; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA.
  • Wu C; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA. Electronic address: wuc3@mail.nih.gov.
  • Dunbar CE; Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA. Electronic address: dunbarc@nhlbi.nih.gov.
Mol Ther ; 27(6): 1074-1086, 2019 06 05.
Article en En | MEDLINE | ID: mdl-31023523

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción Genética / Células Madre Hematopoyéticas / Terapia Genética / Lentivirus / Trasplante de Células Madre Hematopoyéticas / Vectores Genéticos / Hematopoyesis Límite: Animals Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción Genética / Células Madre Hematopoyéticas / Terapia Genética / Lentivirus / Trasplante de Células Madre Hematopoyéticas / Vectores Genéticos / Hematopoyesis Límite: Animals Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos