Glucose impairs angiogenesis and promotes ventricular remodelling following myocardial infarction via upregulation of microRNA-17.

Yan, Meiling; Chen, Kankai; Sun, Rong; Lin, Kaibin; Qian, Xiaolin; Yuan, Minjie; Wang, Yanpeng; Ma, Jian; Qing, Yanwei; Xu, Jun; Wei, Meng; Huang, Dong; Li, Jingbo

Yan, Meiling; Chen, Kankai; Sun, Rong; Lin, Kaibin; Qian, Xiaolin; Yuan, Minjie; Wang, Yanpeng; Ma, Jian; Qing, Yanwei; Xu, Jun; Wei, Meng; Huang, Dong; Li, Jingbo.

Afiliación

Yan M; Heart Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, PR China.
Chen K; Heart Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, PR China.
Sun R; Heart Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, PR China.
Lin K; Heart Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, PR China.
Qian X; Heart Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, PR China.
Yuan M; Heart Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, PR China.
Wang Y; Heart Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, PR China.
Ma J; Heart Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, PR China.
Qing Y; Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen, 518036, PR China.
Xu J; Department of Anesthesia, University of Iowa Hospitals & Clinics, Iowa City, IA, 52242, USA.
Wei M; Heart Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, PR China.
Huang D; Heart Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, PR China. Electronic address: huangdong1004@126.com.
Li J; Heart Center, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, PR China. Electronic address: lijb@sjtu.edu.cn.

Exp Cell Res ; 381(2): 191-200, 2019 08 15.

Article en En | MEDLINE | ID: mdl-31075259

Asunto(s)

Glucosa/farmacología; MicroARNs/genética; Infarto del Miocardio/patología; Infarto del Miocardio/fisiopatología; Neovascularización Fisiológica/efectos de los fármacos; Remodelación Ventricular/efectos de los fármacos; Animales; Células Cultivadas; Diabetes Mellitus Experimental/complicaciones; Diabetes Mellitus Experimental/genética; Diabetes Mellitus Experimental/patología; Diabetes Mellitus Experimental/fisiopatología; Angiopatías Diabéticas/genética; Angiopatías Diabéticas/patología; Angiopatías Diabéticas/fisiopatología; Células Endoteliales de la Vena Umbilical Humana/efectos de los fármacos; Células Endoteliales de la Vena Umbilical Humana/fisiología; Humanos; Masculino; Ratones; Ratones Endogámicos C57BL; Infarto del Miocardio/genética; Neovascularización Fisiológica/genética; Activación Transcripcional/efectos de los fármacos; Activación Transcripcional/genética; Regulación hacia Arriba/efectos de los fármacos; Regulación hacia Arriba/genética; Factor A de Crecimiento Endotelial Vascular/metabolismo; Remodelación Ventricular/genética

Palabras clave

Angiogenesis; Diabetes; MicroRNA-17; Myocardial infarction

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neovascularización Fisiológica / Remodelación Ventricular / MicroARNs / Glucosa / Infarto del Miocardio Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Exp Cell Res Año: 2019 Tipo del documento: Article

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