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Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk.
Zannas, Anthony S; Jia, Meiwen; Hafner, Kathrin; Baumert, Jens; Wiechmann, Tobias; Pape, Julius C; Arloth, Janine; Ködel, Maik; Martinelli, Silvia; Roitman, Maria; Röh, Simone; Haehle, Andreas; Emeny, Rebecca T; Iurato, Stella; Carrillo-Roa, Tania; Lahti, Jari; Räikkönen, Katri; Eriksson, Johan G; Drake, Amanda J; Waldenberger, Melanie; Wahl, Simone; Kunze, Sonja; Lucae, Susanne; Bradley, Bekh; Gieger, Christian; Hausch, Felix; Smith, Alicia K; Ressler, Kerry J; Müller-Myhsok, Bertram; Ladwig, Karl-Heinz; Rein, Theo; Gassen, Nils C; Binder, Elisabeth B.
Afiliación
  • Zannas AS; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany; aszannas@gmail.com binder@psych.mpg.de.
  • Jia M; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514.
  • Hafner K; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514.
  • Baumert J; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710.
  • Wiechmann T; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Pape JC; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Arloth J; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, D-85764 Neuherberg, Germany.
  • Ködel M; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Martinelli S; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Roitman M; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Röh S; Institute of Computational Biology, Helmholtz Zentrum München, D-85764 Neuherberg, Germany.
  • Haehle A; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Emeny RT; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Iurato S; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Carrillo-Roa T; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Lahti J; Department of Chemistry, Institute of Organic Chemistry and Biochemistry, Technische Universität Darmstadt, 64289 Darmstadt, Germany.
  • Räikkönen K; Geisel School of Medicine, Dartmouth College, Lebanon, NH 03755.
  • Eriksson JG; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Drake AJ; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Waldenberger M; Department of Psychology and Logopedics, University of Helsinki, 00100 Helsinki, Finland.
  • Wahl S; Turku Institute for Advanced Studies, University of Turku, 20500 Turku, Finland.
  • Kunze S; Department of Psychology and Logopedics, University of Helsinki, 00100 Helsinki, Finland.
  • Lucae S; Department of General Practice and Primary Health Care, Helsinki University Hospital, University of Helsinki, 00100 Helsinki, Finland.
  • Bradley B; Folkhälsan Research Center, 00290 Helsinki, Finland.
  • Gieger C; University/British Heart Foundation Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom.
  • Hausch F; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, D-85764 Neuherberg, Germany.
  • Smith AK; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, D-85764 Neuherberg, Germany.
  • Ressler KJ; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, D-85764 Neuherberg, Germany.
  • Müller-Myhsok B; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.
  • Ladwig KH; Atlanta Veterans Affairs Medical Center, Decatur, GA 30033.
  • Rein T; Department of Psychiatry and Behavioral Sciences, Emory University Medical School, Atlanta, GA 30322.
  • Gassen NC; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, D-85764 Neuherberg, Germany.
  • Binder EB; Department of Chemistry, Institute of Organic Chemistry and Biochemistry, Technische Universität Darmstadt, 64289 Darmstadt, Germany.
Proc Natl Acad Sci U S A ; 116(23): 11370-11379, 2019 06 04.
Article en En | MEDLINE | ID: mdl-31113877
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Estrés Psicológico / Envejecimiento / Enfermedades Cardiovasculares / Regulación hacia Arriba / FN-kappa B / Proteínas de Unión a Tacrolimus / Epigénesis Genética / Inflamación Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Child, preschool / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Estrés Psicológico / Envejecimiento / Enfermedades Cardiovasculares / Regulación hacia Arriba / FN-kappa B / Proteínas de Unión a Tacrolimus / Epigénesis Genética / Inflamación Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Child, preschool / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article