New insights into the binding mode of pyridine-3-carboxamide inhibitors of E. coli DNA gyrase.

Narramore, Sarah; Stevenson, Clare E M; Maxwell, Anthony; Lawson, David M; Fishwick, Colin W G

Narramore, Sarah; Stevenson, Clare E M; Maxwell, Anthony; Lawson, David M; Fishwick, Colin W G.

Afiliación

Narramore S; School of Chemistry and the Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Stevenson CEM; Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Maxwell A; Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Lawson DM; Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Fishwick CWG; School of Chemistry and the Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK. Electronic address: c.w.g.fishwick@leeds.ac.uk.

Bioorg Med Chem ; 27(16): 3546-3550, 2019 08 15.

Article en En | MEDLINE | ID: mdl-31257079

Asunto(s)

Girasa de ADN/genética; Escherichia coli/metabolismo; Inhibidores de Topoisomerasa II/uso terapéutico; Modelos Moleculares; Relación Estructura-Actividad; Inhibidores de Topoisomerasa II/farmacología

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Girasa de ADN / Escherichia coli / Inhibidores de Topoisomerasa II Tipo de estudio: Prognostic_studies Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido

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