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Single cell analysis of autism patient with bi-allelic NRXN1-alpha deletion reveals skewed fate choice in neural progenitors and impaired neuronal functionality.
Lam, Matti; Moslem, Mohsen; Bryois, Julien; Pronk, Robin J; Uhlin, Elias; Ellström, Ivar Dehnisch; Laan, Loora; Olive, Jessica; Morse, Rebecca; Rönnholm, Harriet; Louhivuori, Lauri; Korol, Sergiy V; Dahl, Niklas; Uhlén, Per; Anderlid, Britt-Marie; Kele, Malin; Sullivan, Patrick F; Falk, Anna.
Afiliación
  • Lam M; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Moslem M; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Bryois J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Pronk RJ; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Uhlin E; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Ellström ID; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Laan L; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Olive J; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Morse R; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Rönnholm H; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Louhivuori L; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Korol SV; Department of Neuroscience, Uppsala University, Uppsala, Sweden.
  • Dahl N; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Uhlén P; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Anderlid BM; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Kele M; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Sullivan PF; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Falk A; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. Electronic address: Anna.Falk@ki.se.
Exp Cell Res ; 383(1): 111469, 2019 10 01.
Article en En | MEDLINE | ID: mdl-31302032
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trastorno Autístico / Proteínas de Unión al Calcio / Eliminación de Gen / Moléculas de Adhesión de Célula Nerviosa / Células Madre Pluripotentes Inducidas / Células-Madre Neurales / Análisis de la Célula Individual / Proteínas del Tejido Nervioso Límite: Humans Idioma: En Revista: Exp Cell Res Año: 2019 Tipo del documento: Article País de afiliación: Suecia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trastorno Autístico / Proteínas de Unión al Calcio / Eliminación de Gen / Moléculas de Adhesión de Célula Nerviosa / Células Madre Pluripotentes Inducidas / Células-Madre Neurales / Análisis de la Célula Individual / Proteínas del Tejido Nervioso Límite: Humans Idioma: En Revista: Exp Cell Res Año: 2019 Tipo del documento: Article País de afiliación: Suecia