Platelet-derived growth factor receptor &#945;/glial fibrillary acidic protein expressing peritumoral astrocytes associate with shorter median overall survival in glioblastoma patients.

Leiss, Lina; Mega, Alessandro; Olsson Bontell, Thomas; Nistér, Monica; Smits, Anja; Corvigno, Sara; Rahman, Mohummad Aminur; Enger, Per Øyvind; Miletic, Hrvoje; Östman, Arne

Platelet-derived growth factor receptor α/glial fibrillary acidic protein expressing peritumoral astrocytes associate with shorter median overall survival in glioblastoma patients.

Leiss, Lina; Mega, Alessandro; Olsson Bontell, Thomas; Nistér, Monica; Smits, Anja; Corvigno, Sara; Rahman, Mohummad Aminur; Enger, Per Øyvind; Miletic, Hrvoje; Östman, Arne.

Afiliación

Leiss L; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Mega A; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Olsson Bontell T; Department of Clinical Pathology and Cytology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Nistér M; Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Acandemy, University of Gothenburg, Sweden.
Smits A; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Corvigno S; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden.
Rahman MA; Department of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden.
Enger PØ; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Miletic H; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Östman A; Department of Biomedicine, University of Bergen, Bergen, Norway.

Glia ; 68(5): 979-988, 2020 05.

Article en En | MEDLINE | ID: mdl-31769546

Asunto(s)

Astrocitos/metabolismo; Neoplasias Encefálicas/mortalidad; Proteína Ácida Fibrilar de la Glía/metabolismo; Glioblastoma/mortalidad; Receptores del Factor de Crecimiento Derivado de Plaquetas/metabolismo; Microambiente Tumoral/fisiología; Adolescente; Adulto; Anciano; Anciano de 80 o más Años; Biomarcadores de Tumor/metabolismo; Neoplasias Encefálicas/genética; Neoplasias Encefálicas/metabolismo; Neoplasias Encefálicas/patología; Niño; Femenino; Proteína Ácida Fibrilar de la Glía/genética; Glioblastoma/genética; Glioblastoma/metabolismo; Glioblastoma/patología; Humanos; Hibridación Fluorescente in Situ; Masculino; Persona de Mediana Edad; Pronóstico; Receptores del Factor de Crecimiento Derivado de Plaquetas/genética; Tasa de Supervivencia; Adulto Joven

Palabras clave

PDGFRα; astrocyte; biomarker; cell subset; glioblastoma; tumor microenvironment

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Astrocitos / Receptores del Factor de Crecimiento Derivado de Plaquetas / Glioblastoma / Microambiente Tumoral / Proteína Ácida Fibrilar de la Glía Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Glia Asunto de la revista: NEUROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Suecia

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google