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Selective and Wash-Resistant Fluorescent Dihydrocodeinone Derivatives Allow Single-Molecule Imaging of µ-Opioid Receptor Dimerization.
Gentzsch, Christian; Seier, Kerstin; Drakopoulos, Antonios; Jobin, Marie-Lise; Lanoiselée, Yann; Koszegi, Zsombor; Maurel, Damien; Sounier, Rémy; Hübner, Harald; Gmeiner, Peter; Granier, Sébastien; Calebiro, Davide; Decker, Michael.
Afiliación
  • Gentzsch C; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
  • Seier K; Institute of Pharmacology and Toxicology, Julius Maximilian University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
  • Drakopoulos A; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
  • Jobin ML; Institute of Pharmacology and Toxicology, Julius Maximilian University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
  • Lanoiselée Y; Institute of Metabolism and Systems Research & Centre of Membrane Proteins and Receptors, University of Birmingham, IBR Tower, Level 2, Edgbaston, Birmingham, B152TT, UK.
  • Koszegi Z; Institute of Metabolism and Systems Research & Centre of Membrane Proteins and Receptors, University of Birmingham, IBR Tower, Level 2, Edgbaston, Birmingham, B152TT, UK.
  • Maurel D; ARPEGE (Pharmacology Screening Interactome) platform facility, Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 141, rue de la Cardonille, 34094, Montpellier Cedex 05, France.
  • Sounier R; Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 141, rue de la Cardonille, 34094, Montpellier Cedex 05, France.
  • Hübner H; Medicinal Chemistry, Department of Chemistry and Pharmacy, Friedrich-Alexander University of Erlangen-Nuremberg, 91058, Erlangen, Germany.
  • Gmeiner P; Medicinal Chemistry, Department of Chemistry and Pharmacy, Friedrich-Alexander University of Erlangen-Nuremberg, 91058, Erlangen, Germany.
  • Granier S; Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 141, rue de la Cardonille, 34094, Montpellier Cedex 05, France.
  • Calebiro D; Institute of Pharmacology and Toxicology, Julius Maximilian University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
  • Decker M; Institute of Metabolism and Systems Research & Centre of Membrane Proteins and Receptors, University of Birmingham, IBR Tower, Level 2, Edgbaston, Birmingham, B152TT, UK.
Angew Chem Int Ed Engl ; 59(15): 5958-5964, 2020 04 06.
Article en En | MEDLINE | ID: mdl-31808251

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Opioides mu / Multimerización de Proteína / Colorantes Fluorescentes / Imagen Individual de Molécula / Hidrocodona Idioma: En Revista: Angew Chem Int Ed Engl Año: 2020 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Opioides mu / Multimerización de Proteína / Colorantes Fluorescentes / Imagen Individual de Molécula / Hidrocodona Idioma: En Revista: Angew Chem Int Ed Engl Año: 2020 Tipo del documento: Article País de afiliación: Alemania