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Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Kimatrai Salvador, Maria; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Viola, Giampietro; Bortolozzi, Roberta; Persoons, Leentje; Balzarini, Jan; Liekens, Sandra; Schols, Dominique.
Afiliación
  • Romagnoli R; Dipartimento di Scienze Chimiche e Farmaceutiche, Università di Ferrara, 44121 Ferrara, Italy. Electronic address: rmr@unife.it.
  • Prencipe F; Dipartimento di Scienze Chimiche e Farmaceutiche, Università di Ferrara, 44121 Ferrara, Italy.
  • Oliva P; Dipartimento di Scienze Chimiche e Farmaceutiche, Università di Ferrara, 44121 Ferrara, Italy.
  • Kimatrai Salvador M; Dipartimento di Scienze Chimiche e Farmaceutiche, Università di Ferrara, 44121 Ferrara, Italy.
  • Brancale A; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, UK.
  • Ferla S; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, UK.
  • Hamel E; Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, Frederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA.
  • Viola G; Dipartimento di Salute della Donna e del Bambino, Laboratorio di Oncoematologia, Università di Padova, 35131 Padova, Italy; Istituto di Ricerca Pediatrica (IRP), Corso Stati Uniti 4, 35128 Padova, Italy.
  • Bortolozzi R; Dipartimento di Salute della Donna e del Bambino, Laboratorio di Oncoematologia, Università di Padova, 35131 Padova, Italy.
  • Persoons L; Rega Institute for Medical Research, KU Leuven, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
  • Balzarini J; Rega Institute for Medical Research, KU Leuven, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
  • Liekens S; Rega Institute for Medical Research, KU Leuven, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
  • Schols D; Rega Institute for Medical Research, KU Leuven, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Bioorg Chem ; 97: 103665, 2020 04.
Article en En | MEDLINE | ID: mdl-32086053
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tubulina (Proteína) / Moduladores de Tubulina / Indoles Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2020 Tipo del documento: Article
Texto completo
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Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tubulina (Proteína) / Moduladores de Tubulina / Indoles Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2020 Tipo del documento: Article