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Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype.
Hanna, Stephanie J; Powell, Wendy E; Long, Anna E; Robinson, Emma J S; Davies, Joanne; Megson, Clare; Howell, Alexandra; Jones, Taz J; Ladell, Kristin; Price, David A; Dayan, Colin M; Williams, Alistair J K; Gillespie, Kathleen M; Wong, F Susan.
Afiliación
  • Hanna SJ; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.
  • Powell WE; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.
  • Long AE; Diabetes and Metabolism, Bristol Medical School, University of Bristol, Bristol, UK.
  • Robinson EJS; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.
  • Davies J; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.
  • Megson C; Diabetes and Metabolism, Bristol Medical School, University of Bristol, Bristol, UK.
  • Howell A; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.
  • Jones TJ; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.
  • Ladell K; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.
  • Price DA; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.
  • Dayan CM; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.
  • Williams AJK; Diabetes and Metabolism, Bristol Medical School, University of Bristol, Bristol, UK.
  • Gillespie KM; Diabetes and Metabolism, Bristol Medical School, University of Bristol, Bristol, UK.
  • Wong FS; Division of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK. wongfs@cardiff.ac.uk.
Diabetologia ; 63(6): 1174-1185, 2020 06.
Article en En | MEDLINE | ID: mdl-32157332

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autoanticuerpos / Linfocitos T CD4-Positivos / Linfocitos T CD8-positivos / Receptor fas / Diabetes Mellitus Tipo 1 Límite: Humans Idioma: En Revista: Diabetologia Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autoanticuerpos / Linfocitos T CD4-Positivos / Linfocitos T CD8-positivos / Receptor fas / Diabetes Mellitus Tipo 1 Límite: Humans Idioma: En Revista: Diabetologia Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido