LUBAC accelerates B-cell lymphomagenesis by conferring resistance to genotoxic stress on B cells.

Jo, Tomoyasu; Nishikori, Momoko; Kogure, Yasunori; Arima, Hiroshi; Sasaki, Katsuhiro; Sasaki, Yoshiteru; Nakagawa, Tomoko; Iwai, Fumie; Momose, Shuji; Shiraishi, Aki; Kiyonari, Hiroshi; Kagaya, Noritaka; Onuki, Tetsuo; Shin-Ya, Kazuo; Yoshida, Minoru; Kataoka, Keisuke; Ogawa, Seishi; Iwai, Kazuhiro; Takaori-Kondo, Akifumi

Jo, Tomoyasu; Nishikori, Momoko; Kogure, Yasunori; Arima, Hiroshi; Sasaki, Katsuhiro; Sasaki, Yoshiteru; Nakagawa, Tomoko; Iwai, Fumie; Momose, Shuji; Shiraishi, Aki; Kiyonari, Hiroshi; Kagaya, Noritaka; Onuki, Tetsuo; Shin-Ya, Kazuo; Yoshida, Minoru; Kataoka, Keisuke; Ogawa, Seishi; Iwai, Kazuhiro; Takaori-Kondo, Akifumi.

Afiliación

Jo T; Department of Hematology and Oncology.
Nishikori M; Department of Molecular and Cellular Physiology, and.
Kogure Y; Department of Hematology and Oncology.
Arima H; Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Sasaki K; Division of Molecular Oncology, National Cancer Center Research Institute, Tokyo, Japan.
Sasaki Y; Department of Hematology and Oncology.
Nakagawa T; Department of Molecular and Cellular Physiology, and.
Iwai F; Department of Molecular and Cellular Physiology, and.
Momose S; Department of Molecular and Cellular Physiology, and.
Shiraishi A; Department of Hematology and Oncology.
Kiyonari H; Department of Pathology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan.
Kagaya N; Laboratories for Animal Resource Development and.
Onuki T; Laboratories for Animal Resource Development and.
Shin-Ya K; Laboratories for Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
Yoshida M; National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan.
Kataoka K; Seed Compound Exploratory Unit for Drug Discovery Platform, RIKEN Center for Sustainable Resource Science, Wako, Japan.
Ogawa S; National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan.
Iwai K; Biotechnology Research Center and Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Tokyo, Japan.
Takaori-Kondo A; Seed Compound Exploratory Unit for Drug Discovery Platform, RIKEN Center for Sustainable Resource Science, Wako, Japan.

Blood ; 136(6): 684-697, 2020 08 06.

Article en En | MEDLINE | ID: mdl-32325488

Asunto(s)

Apoptosis/genética; Linfocitos B/enzimología; Transformación Celular Neoplásica/genética; Linfoma de Células B Grandes Difuso/etiología; Complejos Multiproteicos/fisiología; Ubiquitina-Proteína Ligasas/genética; Animales; Linfocitos B/patología; Proteínas Portadoras/fisiología; Daño del ADN; Regulación Neoplásica de la Expresión Génica; Xenoinjertos; Humanos; Péptidos y Proteínas de Señalización Intracelular/fisiología; Linfoma de Células B Grandes Difuso/enzimología; Linfoma de Células B Grandes Difuso/genética; Ratones; Ratones Transgénicos; Mutación Missense; Factor 88 de Diferenciación Mieloide/genética; Factor 88 de Diferenciación Mieloide/fisiología; FN-kappa B/metabolismo; Trasplante de Neoplasias; Polimorfismo de Nucleótido Simple; Poliubiquitina/biosíntesis; Procesamiento Proteico-Postraduccional; Factores de Transcripción/fisiología; Transcriptoma; Ubiquitina-Proteína Ligasas/análisis; Ubiquitina-Proteína Ligasas/fisiología; Ubiquitinación; Ubiquitinas/fisiología

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos B / Transformación Celular Neoplásica / Linfoma de Células B Grandes Difuso / Apoptosis / Ubiquitina-Proteína Ligasas / Complejos Multiproteicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Blood Año: 2020 Tipo del documento: Article

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