Hypothermic treatment for neonatal asphyxia in low-resource settings using phase-changing material-An easy to use and low-cost method.
Acta Paediatr
; 110(1): 85-93, 2021 01.
Article
en En
| MEDLINE
| ID: mdl-32347576
ABSTRACT
AIM:
To evaluate whether phase-changing material can be used for therapeutic hypothermia of asphyxiated newborns in low-resource settings.METHODS:
Prospective interventional study of asphyxiated term infants fulfilling criteria for hypothermia treatment at Vietnam National Children's Hospital from September 2014 to September 2016. Hypothermia was induced within 6 hours after birth and maintained for 72 hours by a phase-changing material mattress with melting point of 32°C. Rectal temperature was continuously measured, and deviations from target temperature range 33.5-34.5°C were recorded.RESULTS:
In total 52 infants (mean gestational age 39.3 ± 1.1 weeks) included and cooled, the median temperature at initiation of cooling was 35.3 (IQR 34.5-35.9)°C. The median time to reach target temperature was 2.5 (IQR 2-3) hours. The mean temperature during the cooling phase was 33.95 ± 0.2°C. Throughout the cooling phase, the target temperature range (33.5-34.5°C) was maintained more than 80% of the time. Rate of rewarming was 0.5 ± 0.14°C/hour.CONCLUSION:
Phase-changing material can be used as an effective cooling method. Though not a servo-controlled system, it is easy to induce hypothermia, maintain target temperature and rewarm infants in a slow and controlled manner without need for frequent changes and minimum risk of skin injury.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Asfixia Neonatal
/
Hipoxia-Isquemia Encefálica
/
Hipotermia
/
Hipotermia Inducida
Tipo de estudio:
Health_economic_evaluation
/
Observational_studies
Límite:
Child
/
Humans
/
Infant
/
Newborn
País/Región como asunto:
Asia
Idioma:
En
Revista:
Acta Paediatr
Año:
2021
Tipo del documento:
Article
País de afiliación:
Vietnam